IP Library Granted Patent US 8,237,112
Granted Patent B2
US 8,237,112 · App. 13/028,481 · Granted Aug 7, 2012

Method and apparatus for time-of-flight mass spectrometry

Assignee: Jeol Ltd.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,237,112
App. No.
13/028,481
Granted
Aug 7, 2012
Kind
B2
Abstract

A method and apparatus for time-of-flight (TOF) mass spectrometry. The apparatus improves the ion focusing properties in an orthogonal direction and permits connection with an orthogonal-acceleration ion source for improvement of sensitivity. The apparatus comprises an ion source for emitting ions in a pulsed manner, an analyzer for realizing a helical trajectory, and a detector for detecting the ions. The analyzer is composed of plural laminated toroidal electric fields to realize the helical trajectory.

Claims (17)

1. A time-of-flight mass spectrometer comprising:

a single ion source for producing ions;

means for accelerating the ions in a pulsed manner;

a time-of-flight mass analyzer which is composed of plural electric sector fields and in which the ions are made to travel in a helical trajectory;

at least two detectors, one of the detectors acting to measure times of flight of the ions which are generated and accelerated out of the ion source and made to travel straight, the other or others of the detectors acting to measure times of flight of the ions which are made to travel in a helical trajectory by the plural electric sector fields, further comprising an ion optical system capable of completely satisfying spatial and time focusing conditions whenever a revolution is made, wherein the sample is ionized in said ion source by a MALDI.

2. A time of flight mass spectrometer comprising:

a single ion source for producing ions;

means for accelerating the ions in a pulsed manner;

a time-of-flight mass analyzer which is composed of plural electric sector fields and in which the ions are made to travel in a helical trajectory;

at least two detectors, one of the detectors acting to measure times of flight of the ions which are generated and accelerated out of the ion source and made to travel straight, the other or others of the detectors acting to measure times of flight of the ions which are made to travel in a helical trajectory by the plural electric sector fields, wherein the same sample is measured alternately by a linear time-of-flight mass analyzer and a helical trajectory time-of-flight mass analyzer.

3. A time-of-flight mass spectrometer comprising:

a single ion source for producing ions;

means for accelerating the ions in a pulsed manner;

a time-of-flight mass analyzer which is composed of plural electric sector fields and in which the ions are made to travel in a helical trajectory;

at least two detectors, one of the detectors acting to measure times of flight of the ions which are generated and accelerated out of the ion source and made to travel straight, the other or others of the detectors acting to measure times of flight of the ions which are made to travel in a helical trajectory by the plural electric sector fields, wherein the same sample is measured by a linear time-of-flight mass analyzer and a helical trajectory time-of-flight mass analyzer at the same time.

4. A time-of-flight mass spectrometer as set forth in claim 2 or 3 , wherein ions are ionized in said ion source by illuminating a sample on a conductive sample plate with laser light.

5. A time-of-flight mass spectrometer as set forth in claim 2 or 3 , wherein said means for accelerating the ions uses delayed extraction technique.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 21, 2011
From: SATO, TAKAYA; TOYODA, MICHISATO; ISHIHARA, MORIO
To: JEOL LTD.
Reel/Frame 025838/0686 →
Priority Claims (3)
JP 2004-151473 · May 21, 2004 · national
JP 2005-131106 · Apr 28, 2005 · national
WO PCT/JP2005/008951 · May 17, 2005 · international
Continuity (3)
Division 12390710 · Feb 23, 2009
Division 10592299 · Sep 8, 2006
Related Publication 20110133073A1 · Jun 9, 2011