Abdominal wall treatment devices
View Patent ↗Devices and methods for treating or repairing openings in an body wall are provided. The devices and methods can include acellular tissue matrices. The tissue matrices can be positioned within the abdominal opening and can be used to close the opening.
1. An abdominal or fascia treatment device, comprising:
a sheet of synthetic polymeric material; and
an acellular tissue matrix attached to and extending from a peripheral border of the sheet of synthetic polymeric material such that the acellular tissue matrix can be secured to tissues surrounding a defect in a wall of a body cavity to close the body cavity without attaching the sheet of synthetic polymeric material to tissue,
wherein the acellular tissue matrix defines a peripheral portion of the abdominal or fascia treatment device, and the sheet of synthetic polymeric material defines a central portion of the abdominal or fascia treatment device, and
wherein the sheet of synthetic polymeric material includes an elongated opening extending across a portion of the sheet of synthetic polymeric material, the elongated opening being configured to provide access to the body cavity in an open configuration and close the body cavity in a closed configuration.
2. The device of claim 1 , wherein an ultimate strength of the sheet of synthetic polymeric material differs from an ultimate strength of the acellular tissue matrix by less than 20%.
3. The device of claim 1 , wherein an elastic modulus of the sheet of synthetic polymeric material differs from an elastic modulus of the acellular tissue matrix by less than 20%.
4. The device of claim 1 , wherein the acellular tissue matrix is a dermal acellular tissue matrix.
5. The device of claim 4 , wherein the dermal tissue matrix is a human tissue matrix.
6. The device of claim 4 , wherein the dermal tissue matrix is a porcine tissue matrix.
7. The device of claim 1 , wherein the acellular tissue matrix includes preformed holes disposed on each side of the sheet of synthetic polymeric material.
8. An abdominal or fascia treatment device, comprising:
a sheet of synthetic polymeric material, the sheet of synthetic polymeric material being without perforations at a central portion of the sheet of synthetic polymeric material except for an elongated opening extending across a portion of the sheet of synthetic polymeric material; and
an acellular tissue matrix attached to and extending from a peripheral border of the sheet of synthetic polymeric material such that the acellular tissue matrix can be secured to tissues surrounding a defect in a wall of a body cavity to close the body cavity without attaching the sheet of synthetic polymeric material to tissue,
wherein the acellular tissue matrix defines a peripheral portion of the abdominal or fascia treatment device, and the sheet of synthetic polymeric material defines a central portion of the abdominal or fascia treatment device, and
wherein the elongated opening is configured to provide access to the body cavity in an open configuration and close the body cavity in a closed configuration.
9. The device of claim 7 , wherein the preformed holes are reinforced.
10. The device of claim 9 , wherein the reinforced holes include an adhesive.
11. The device of claim 10 , wherein the adhesive includes a cyanoacrylate adhesive.
12. The device of claim 10 , wherein the adhesive includes fibrin.
13. A method of treating an abdominal or fascia defect, comprising:
positioning a sheet of synthetic polymeric material of an abdominal or fascia treatment device in or on a defect in a body cavity, wherein an acellular tissue matrix is attached to and extends from a peripheral border of the sheet of synthetic polymeric material such that the acellular tissue matrix can be secured to tissues surrounding the defect in a wall of the body cavity to close the body cavity without attaching the sheet of synthetic polymeric material to tissue, wherein the acellular tissue matrix defines a peripheral portion of the abdominal or fascia treatment device, and the sheet of synthetic polymeric material defines a central portion of the abdominal or fascia treatment device, and wherein the sheet of synthetic polymeric material includes an elongated opening extending across a portion of the sheet of synthetic polymeric material, the elongated opening being configured to provide access to the body cavity in an open configuration and close the body cavity in a closed configuration; and
securing the acellular tissue matrix to tissue surrounding a peripheral border of the defect to close the defect.
14. The method of claim 13 , further including removing the sheet of synthetic polymeric material at a later time while leaving the acellular tissue matrix attached to the tissues surrounding the peripheral border of the abdominal defect.
15. The method of claim 14 , further including closing the defect in the body cavity after removing the sheet of synthetic polymeric material by attaching remaining portions of the acellular tissue matrix to one another.
16. The method of claim 15 , wherein attaching the remaining portions of the acellular tissue matrix to one another includes passing sutures through preformed holes in the acellular tissue matrix.
17. The method of claim 16 , wherein the preformed holes are reinforced.
18. The method of claim 17 , wherein the reinforced holes include an adhesive.
19. The method of claim 18 , wherein the adhesive includes a cyanoacrylate adhesive.
20. The method of claim 18 , wherein the adhesive includes fibrin.