Breast tissue models, materials, and methods
Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In one instances, the human breast tissue model comprises a simulated breast tissue comprising a mixture of a silicone foam and a silicone oil and a simulated skin layer covering the simulated breast tissue, where the simulated breast tissue and the simulated skin layer are sized and shaped to mimic a natural human breast. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.
1. A polysiloxane mixture for simulating human biological tissue, the mixture comprising:
a silicone foam, wherein the silicone foam comprises a closed cell silicone foam; and
a silicone oil, wherein the silicone oil comprises a low molecular weight silicone oil;
the silicone foam and the silicone oil combined in a manner such that the resulting mixture has physical material properties simulating a natural human biological tissue.
2. The polysiloxane mixture of claim 1 , wherein the silicone foam is present in an amount of about 10 to 45 percent by weight of a total mixture weight, and the silicone oil is present in an amount of about 55 to 90 percent by weight of the total mixture weight.
3. The polysiloxane mixture of claim 2 , wherein the silicone foam is present in an amount of about 25 percent by weight of the total mixture weight and the silicone oil is present in an amount of amount of about 75 percent by weight of the total mixture weight.
4. The polysiloxane mixture of claim 1 , wherein the silicone oil has a viscosity of about 30 to 500 centipoise.
5. The polysiloxane mixture of claim 1 , further comprising a silicone thermoset.
6. The polysiloxane mixture of claim 5 , wherein the silicone foam and the silicone thermoset comprise a platinum catalyzed silicone.
7. The polysiloxane mixture of claim 5 , wherein the silicone foam, the silicone oil, and the silicone thermoset are combined in a manner such that the resulting mixture has physical material properties simulating natural human breast tissue.
8. A human breast tissue model comprising:
simulated breast tissue comprising a mixture of a silicone foam and a silicone oil; and
a simulated skin layer covering the simulated breast tissue, the simulated skin layer comprising a first silicone thermoset;
wherein the simulated breast tissue and the simulated skin layer are sized and shaped to mimic a natural human breast.
9. The human breast tissue model of claim 8 , further comprising at least one simulated pathological structure imbedded within the simulated breast tissue, the at least one simulated pathological structure comprising a material different than the simulated breast tissue.
10. The human breast tissue model of claim 9 , wherein the at least one simulated pathological structure simulates a pathology selected from a group consisting of a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.
11. The human breast tissue model of claim 9 , wherein the at least one simulated pathological structure comprises a second silicone thermoset.
12. The human breast tissue model of claim 11 , wherein the second silicone thermoset of the at least one simulated pathological structure has a shore hardness of about 10 A.
13. The human breast tissue model of claim 8 , further comprising at least one simulated anatomical structure imbedded within the simulated breast tissue at an anatomically appropriate location.
14. The human breast tissue model of claim 13 , wherein the at least one simulated anatomical structure simulates an anatomical structure selected from a group consisting of a lymph node, a pectoralis muscle, and a rib.
15. The human breast tissue model of claim 8 , wherein the first silicone thermoset of the simulated skin layer has a shore hardness of about 0010.
16. The human breast tissue model of claim 8 , wherein the silicone oil has a viscosity of about 50 to 300 centipoise.
17. The human breast tissue model of claim 8 , further comprising a fastener attached to a portion of the human breast tissue model, the fastener configured to affix the human breast tissue model to a base.
18. The human breast tissue model of claim 17 , wherein the fastener is attached to the portion of the human breast tissue with an adhesive.
19. A method of manufacturing a biological tissue phantom, the method comprising:
mixing a silicone oil with a silicone foam to form a blend;
pouring the blend into a mold;
stirring the blend until a foaming reaction starts; and
allowing the blend to cure, wherein the cured blend has physical material properties simulating a natural human biological tissue.
20. The method of claim 19 , further comprising adding a silicone thermoset to reduce the size and quantity of the foam cells.
21. The method of claim 19 , wherein the silicone foam is a two-component platinum silicone foam.
22. The method of claim 19 , wherein the silicone oil is a low molecular weight silicone oil.
23. The method of claim 19 , wherein the amount of silicone oil that is mixed is about three times the amount of the silicone foam.