IP Library Granted Patent US 8,465,540
Granted Patent B2
US 8,465,540 · App. 13/033,023 · Granted Jun 18, 2013

Stent for the positioning and anchoring of a valvular prosthesis

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Quick Facts
Patent No.
US 8,465,540
App. No.
13/033,023
Granted
Jun 18, 2013
Kind
B2
Abstract

The present invention relates to a stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis fastened to a stent will occur relative the stent in the implanted state of the stent, even given the peristaltic motion of the heart, the stent according to the invention comprises at least one fastening portion via which the valvular prosthesis is connectable to the stent. The stent further comprises positioning arches and retaining arches, whereby at least one positioning arch is connected to at least one retaining arch.

Claims (29)

1. An expandable stent for the positioning and anchoring of a valvular prosthesis in an implantation site, the stent comprising: a plurality of positioning arches configured to be positioned within a plurality of pockets of a native heart valve and positioned on a first side of a plurality of native heart valve leaflets, a plurality of retaining arches configured to be positioned on a second side of the plurality of native heart valve leaflets opposite the first side, and a plurality of radial arches, each radial arch substantially circumferentially aligned with one of the plurality of positioning arches, wherein respective arms of each of the plurality of retaining arches include a plurality of bending edges, each of the plurality of bending edges defining a bending point between two adjacent arm segments.

2. The expandable stent according to claim 1 , wherein each of the plurality of positioning arches includes a substantially U-shaped or V-shaped structure.

3. The expandable stent according to claim 1 , further including a collapsed mode when being introduced into a patient's body and an expanded mode when implanted.

4. The expandable stent according to claim 1 , wherein each of the plurality of positioning arches and the plurality of retaining arches consists essentially of three arches.

5. The expandable stent according to claim 1 , wherein each of the plurality of positioning arches and each of the plurality of radial arches includes a closed end, and the closed end of a respective positioning arch is substantially circumferentially aligned with respect to the closed end of an associated radial arch.

6. The expandable stent according to claim 5 , wherein the closed end of each of the plurality of retaining arches extends in a first axial direction of the stent and the closed end of each of the plurality of radial arches extends in a second axial direction of the stent, opposite the first axial direction.

7. The expandable stent according to claim 1 , further comprising a plurality of auxiliary arches, each interspaced between two adjacent retaining arches and including a first arm connected at a first end thereof to a first retaining arch and a second arm connected at a first end thereof to a second retaining arch, wherein the first and second arms of each of the plurality of auxiliary arches include respective second ends connected to at least one annular collar.

8. The expandable stent according to claim 1 , wherein each of the plurality of positioning arches includes first and second arms joined to one another at a head portion, and wherein the expandable stent further comprises a plurality of leaflet guard arches, each interspaced between the two arms of one of the plurality of positioning arches and including a first arm and a second arm, wherein the first and second arms of each of the plurality of leaflet guard arches are joined to one another at a head portion.

9. The expandable stent according to claim 8 , wherein each radial arch includes first and second arms joined to one another at a head portion.

10. The expandable stent according to claim 9 , wherein each of the plurality of radial arches is joined to a respective one of the plurality of leaflet guard arches.

11. The expandable stent according to claim 1 , further including at least one annular collar connected to each of the respective retaining arches.

12. The expandable stent according to claim 11 , further comprising a structure of lattice cells formed by a plurality of struts disposed circumferentially between respective arms of two adjacent retaining arches.

13. The expandable stent according to claim 11 , further comprising a plurality of notches uniformly distributed around a proximalmost portion of the at least one annular collar.

14. The expandable stent according to claim 1 , wherein a valvular prosthesis is connected to the stent via at least one suture.

15. The expandable stent according to claim 14 , wherein the valvular prosthesis is made from pericardium.

16. The expandable stent according to claim 1 , wherein each of the plurality of positioning arches includes first and second arms joined to one another at a head portion projecting toward a first end of the stent, and wherein each of the plurality of radial arches includes first and second arms joined to one another at a head portion projecting toward a second end of the stent, opposite the first end.

17. The expandable stent according to claim 16 , wherein the first and second arms of each radial arch include: a first portion extending in the first direction toward a head portion of a respective one of the plurality of positioning arches; and a second portion extending in the second direction away from the head portion of a respective one of the plurality of positioning arches; wherein the respective second portions of the first and second arms of each radial arch are connected to one another to form the head portion of the radial arch.

18. An expandable stent for the positioning and anchoring of a valvular prosthesis in an implantation site, the stent comprising:

a plurality of positioning arches configured to be positioned within a plurality of pockets of a native heart valve and positioned on a first side of a plurality of native heart valve leaflets, wherein each of the plurality of positioning arches includes first and second arms joined to one another at a head portion;

a plurality of retaining arches configured to be positioned on a second side of the plurality of native heart valve leaflets opposite the first side, wherein respective arms of each of the plurality of retaining arches include a plurality of bending edges, each of the plurality of bending edges defining a bending point between two adjacent arm segments and

a plurality of leaflet guard arches, each leaflet guard arch interspaced between the two arms of one of the plurality of positioning arches and including a first arm and a second arm, wherein the first and second arms of each of the plurality of leaflet guard arches are joined to one another at a head portion.

19. The expandable stent according to claim 18 , further including a plurality of radial arches, each radial arch substantially circumferentially aligned with one of the plurality of positioning arches, each radial arch including first and second arms joined to one another at a head portion.

20. The expandable stent according to claim 19 , wherein each of the plurality of radial arches is joined to a respective one of the plurality of leaflet guard arches.

21. An expandable stent for the positioning and anchoring of a valvular prosthesis in an implantation site, the stent comprising:

a plurality of positioning arches configured to be positioned within a plurality of pockets of a native heart valve and positioned on a first side of a plurality of native heart valve leaflets;

a plurality of retaining arches configured to be positioned on a second side of the plurality of native heart valve leaflets opposite the first side, wherein respective arms of each of the plurality of retaining arches include a plurality of bending edges, each of the plurality of bending edges defining a bending point between two adjacent arm segments and

at least one annular collar connected to each of the respective retaining arches.

22. The expandable stent according to claim 21 , further comprising a structure of lattice cells formed by a plurality of struts disposed circumferentially between respective arms of two adjacent retaining arches.

23. The expandable stent according to claim 21 , further comprising a plurality of notches uniformly distributed around a proximalmost portion of the at least one annular collar.

Assignments (7)
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jan 28, 2022
From: JENAVALVE TECHNOLOGY, INC.
To: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
Reel/Frame 058894/0788 →
RELEASE OF SECURITY INTEREST Recorded Jan 21, 2022
From: KREOS CAPITAL V (UK) LIMITED
To: JENAVALVE TECHNOLOGY, INC.
Reel/Frame 058802/0452 →
SECURITY INTEREST Recorded Dec 4, 2018
From: JENAVALVE TECHNOLOGY, INC.
To: KREOS CAPITAL V (UK) LIMITED
Reel/Frame 048325/0368 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 29, 2016
From: JVT RESEARCH & DEVELOPMENT CORPORATION
To: JENAVALVE TECHNOLOGY, INC.
Reel/Frame 038276/0168 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 28, 2016
From: JENAVALVE TECHNOLOGY GMBH
To: JVT RESEARCH & DEVELOPMENT CORPORATION
Reel/Frame 038279/0820 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2014
From: JENAVALVE TECHNOLOGY, INC.
To: JENAVALVE TECHNOLOGY GMBH
Reel/Frame 033084/0369 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 5, 2011
From: STRAUBINGER, HELMUT; JUNG, JOHANNES; GIRARD, MICHAEL J.; MAYER, ARNULF
To: JENAVALVE TECHNOLOGY, INC.
Reel/Frame 026707/0635 →