DEVICES, SYSTEMS, AND METHODS FOR CLOSING A HOLE IN CARDIAC TISSUE
Devices, systems, and methods for closing a hole in cardiac tissue. In at least one embodiment of a device for occluding a tissue aperture of the present disclosure, the device comprises a body comprising a proximal end, a distal end, a sidewall, and at least one marker, the body tapered towards the distal end and defining a body aperture therethrough capable of receiving an elongated member. In at least one embodiment, the body further comprises a diaphragm positioned at or near one or more of the proximal end of the body and/or the distal end of the body. In another embodiment, the diaphragm comprises a plurality of sheaths, wherein the plurality of sheaths sealably obstruct the body aperture.
1 . A device for occluding a tissue aperture, the device comprising:
a body comprising a proximal end, a distal end, a sidewall, and at least one marker, the body tapered towards the distal end and defining a body aperture therethrough capable of receiving an elongated member.
2 . The device of claim 1 , wherein the device is comprised of a material selected from the group consisting of polytetratluoroethylene (PTFE), expanded PTFE, polypropylene, silicone rubber, poly(lactic-co-glycolic acid), and a combination of one or more of the foregoing materials.
3 . The device of claim 1 , wherein the at least one marker comprises a first marker positioned at or near the proximal end of the body and a second marker positioned at or near the distal end of the body.
4 . The device of claim 1 , wherein the at least one marker is comprised of a radiopaque material selected from the group consisting of platinum, stainless steel, nitinol, and chromium-cadmium, or a combination thereof.
5 . The device of claim 1 , wherein the body is sized and shaped to define a notch transverse to the body aperture, the notch forming a channel between the body aperture and a portion of the sidewall.
6 . The device of claim 5 , wherein the notch is sized and shaped to allow passage of a portion of the elongated member therethrough.
7 . The device of claim 1 , further comprising:
a groove defined in the sidewall of the body, the groove sized and shaped to engage tissue at the tissue aperture.
8 . The device of claim 1 , wherein the body further comprises a diaphragm positioned at or near one or more of the proximal end of the body and/or the distal end of the body.
9 . The device of claim 8 , wherein the diaphragm comprises a plurality of sheaths, wherein the plurality of sheaths sealably obstruct the body aperture.
10 . The device of claim 1 , wherein the body is biodegradable.
11 . A system for occluding a tissue aperture, the system comprising:
a device for occluding a tissue aperture, the device comprising:
a body comprising a proximal end, a distal end, a sidewall, and at least one marker, the body tapered towards the distal end and defining a body aperture therethrough capable of receiving an elongated member; and
an elongated member positioned within the body aperture.
12 . The system of claim 11 , wherein the elongated member is selected from the group comprising a wire, a pacing lead, and a catheter.
13 . The system of claim 11 , wherein the body is sized and shaped to define a notch transverse to the body aperture, the notch forming a channel between the body aperture and a portion of the sidewall, wherein the notch is sized and shaped to allow passage of a portion of the elongated member therethrough.
14 . The system of claim 11 , wherein the device further comprises:
a groove defined in the sidewall of the body, the groove sized and shaped to engage the tissue aperture.
15 . The system of claim 11 , wherein the body further comprises:
a diaphragm positioned at or near the proximal of the body, the diaphragm comprising a plurality of sheaths configured to sealably obstruct the body aperture.
16 . The system of claim 11 , wherein the system further comprises:
a conduit configured to reversibly engage the device.
17 . The system of claim 16 , wherein the conduit is configured to decrease a cross-sectional area of a portion of the device.
18 . A method for occluding a tissue aperture comprising the steps of:
inserting an occlusion device into a mammalian body, the occlusion device comprising a body comprising a proximal end, a distal end, a sidewall, and at least one marker, the body tapered towards the distal end and defining a body aperture therethrough capable of receiving an elongated member; and
positioning the occlusion device so that a portion of the occlusion device engages a tissue aperture of the mammalian body to occlude the tissue aperture.
19 . The method of claim 18 , wherein the positioning step is performed using a conduit configured to reversibly engage the device.
20 . The method of claim 18 , further comprising the step of:
positioning an elongated member within the body aperture so that at least a portion of the elongated member extends past a distal end of the device.