IP Library Granted Patent US 8,506,517
Granted Patent B2
US 8,506,517 · App. 13/036,358 · Granted Aug 13, 2013

Flow control method and device

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Quick Facts
Patent No.
US 8,506,517
App. No.
13/036,358
Granted
Aug 13, 2013
Kind
B2
Abstract

An arterio-venous graft ( 16 ) is provided with a constriction device ( 20 ) near its arterial end. The constriction device ( 20 ) is used to reduce the flow through the AV graft under normal conditions and to relieve the constriction when high flow through the AV graft is required, such as for vascular access for hemodialysis.

Claims (16)

1. A method for treating renal dysfunction in a patient, the method comprising:

implanting a device in the patient to partially and controllably constrict a renal artery;

adjusting, externally to a body of the patient, a degree of constriction applied by the device to the renal artery; and

controlling the degree of constriction applied by the device to maintain the degree of constriction, wherein the device comprises:

an implantable housing;

a motor disposed within the implantable housing;

a drive shaft coupled to the motor;

a constriction applicator disposed within the implantable housing, the constriction applicator configured to control a fluid flow in the renal artery; and

a transmission coupled to the drive shaft and the constriction applicator, the transmission configured to covert a rotation of the drive shaft for controlling a linear motion of a constriction applicator,

wherein the constriction applicator comprises:

a first member configured to move linearly in a direction substantially perpendicular to the fluid flow in the renal artery; and

a second member coupled to the first member, the second member configured to apply an increasing amount of pressure as the first member is driven away from the transmission and toward the renal artery,

wherein the constriction applicator further comprises a third member forming an outer surface or an outer edge of the housing,

wherein the first member is a rod, the second member is a bar and the third member is a fine titanium membrane.

2. The method of claim 1 wherein the motor is an electrical micromotor.

3. The method of claim 1 further comprising a receiver disposed within the implantable housing, the receiver coupled to the constriction applicator to selectively adjust a degree of constriction applied by the constriction applicator.

Assignments (13)
RELEASE OF SECURITY INTEREST Recorded Dec 30, 2021
From: SLR INVESTMENT CORP. (F/K/A SOLAR CAPITAL LTD.)
To: APOLLO ENDOSURGERY US, INC.; APOLLO ENDOSURGERY INTERNATIONAL, LLC; APOLLO ENDOSURGERY, INC.; LPATH THERAPEUTICS INC.
Reel/Frame 058599/0297 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Apr 15, 2019
From: APOLLO ENDOSURGERY US, INC.
To: SOLAR CAPITAL LTD., AS COLLATERAL AGENT
Reel/Frame 048885/0687 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS Recorded Jan 4, 2019
From: ATHYRIUM OPPORTUNITIES II ACQUISITION LP, AS ADMINISTRATIVE AGENT
To: APOLLO ENDOSURGERY US, INC.
Reel/Frame 048012/0902 →
CHANGE OF NAME Recorded Mar 27, 2017
From: APOLLO ENDOSURGERY, INC.
To: APOLLO ENDOSURGERY US, INC.
Reel/Frame 042106/0912 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Dec 30, 2016
From: APOLLO ENDOSURGERY US, INC.
To: ATHYRIUM OPPORTUNITIES II ACQUISITION LP, AS ADMINISTRATIVE AGENT
Reel/Frame 041224/0821 →
CHANGE OF NAME Recorded Jul 2, 2015
From: ALLERGAN MEDICAL SA
To: ALLERGAN MEDICAL SARL
Reel/Frame 036077/0187 →
TERMINATION OF PATENT SECURITY INTEREST (RECORDED ON 12/3/13 AT REEL/FRAME 031756/0729 AND ON 1/2/14 AT REEL/FRAME 031910/0460) Recorded Mar 2, 2015
From: OXFORD FINANCE LLC, AS AGENT
To: APOLLO ENDOSURGERY, INC.
Reel/Frame 035120/0740 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Mar 2, 2015
From: APOLLO ENDOSURGERY, INC.
To: ATHYRIUM OPPORTUNITIES II ACQUISITION LP, AS ADMINISTRATIVE AGENT
Reel/Frame 035120/0843 →
CHANGE OF NAME Recorded Nov 20, 2014
From: ENDOART S.A.
To: ALLERGAN MEDICAL SA
Reel/Frame 034350/0546 →
CORRECTIVE ASSIGNMENT TO CORRECT THE EXECUTION DATE PREVIOUSLY RECORDED ON REEL 031861 FRAME 0521. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT OF ASSIGNORS INTEREST. Recorded Jan 7, 2014
From: ALLERGAN MEDICAL SARL
To: APOLLO ENDOSURGERY, INC.
Reel/Frame 031925/0046 →
SECURITY AGREEMENT Recorded Jan 2, 2014
From: APOLLO ENDOSURGERY, INC.
To: OXFORD FINANCE LLC, AS AGENT
Reel/Frame 031910/0460 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2013
From: ALLERGAN MEDICAL SARL
To: APOLLO ENDOSURGERY, INC.
Reel/Frame 031861/0521 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 22, 2013
From: STERGIOPULOS, NIKOS
To: ENDOART S.A.
Reel/Frame 031453/0623 →