Hernia Patch
Surgical implants which include a biocompatible substrate and at least one grip member capable of transitioning between a first non-gripping configuration and a second gripping configuration.
1 . A surgical implant comprising:
a biocompatible substrate; and
at least one grip member capable of transitioning between a first non-gripping configuration and a second gripping configuration.
2 . The surgical implant of claim 1 wherein the grip member is interwoven with the biocompatible substrate.
3 . The surgical implant of claim 1 wherein the grip member comprises a shape memory material.
4 . The surgical implant of claim 3 wherein the shape memory material transitions from the first configuration to the second configuration between about 20° C. and about 40° C.
5 . The surgical implant of claim 3 wherein the shape memory material is selected on the group consisting of polymers and metal alloys.
6 . The surgical implant of claim 5 wherein the shape memory polymer is selected from the group consisting of polyurethanes, poly(styrene-butadiene) block copolymers, polynorbornenes, polycaprolactones, polydioxanones, polylactic acids, oligo (p-dioxanone) diols, oligo (epsilon caprolactone) diols, polytrimethylene carbonates, and combinations thereof.
7 . The surgical implant of claim 5 wherein the shape memory polymer comprises copolymers selected from the group consisting of poly(epsilon-caprolactone) dimethacrylate-poly (n-butyl acrylate), poly(epsilon caprolactone) diol-poly(p-dioxanone) diol, and combinations thereof.
8 . The surgical implant of claim 3 wherein the shape memory material comprises a light-activated shape memory polymer.
9 . The surgical implant of claim 3 wherein the shape memory material comprises a heat-activated shape memory material.
10 . The surgical implant of claim 3 wherein the shape memory material comprises an electrically activated shape memory material.
11 . The surgical implant of claim 5 wherein the shape memory metal alloy comprises an alloy selected from the group consisting of copper-zinc-aluminum-nickel alloys, copper-aluminum-nickel alloys, zinc-copper-gold-iron alloys, and nickel-titanium (NiTi) alloys.
12 . The surgical implant of claim 1 wherein the biocompatible substrate is selected from the group consisting of a foam, film, tissue scaffold, pledget, buttress, mesh and combinations thereof.
13 . The surgical implant of claim 1 wherein the biocompatible substrate comprises a soft tissue repair device.
14 . The surgical implant of claim 1 wherein the biocompatible substrate comprises a surgical mesh.
15 . The surgical implant of claim 1 further comprising a bioactive agent.
16 . The surgical implant of claim 1 wherein the first non-gripping configuration of the grip member is positioned substantially parallel to a longitudinal axis of the biocompatible substrate.
17 . The surgical implant of claim 1 wherein the second gripping configuration of the grip member extends substantially perpendicular from a longitudinal axis of the biocompatible substrate.
18 . The surgical implant of claim 1 wherein the second gripping configuration comprises a generally L-shaped grip member.
19 . The surgical implant of claim 1 wherein the second gripping configuration comprises a generally J-shaped grip member.
20 . A method of making a surgical implant, the method comprising:
conditioning at least one grip member to transition between a first, non-gripping configuration and a second, gripping configuration; and
incorporating the at least one grip member into a biocompatible substrate.
21 . The method of claim 20 wherein conditioning the at least one grip member comprises heating the grip member, deforming the grip member to a non-gripping configuration and cooling the grip member.
22 . The method of claim 20 wherein incorporating the at least one grip member into a biocompatible substrate is selected from the group consisting of knitting, weaving, braiding, and combinations thereof.
23 . The method of claim 20 wherein the at least one grip member comprises a shape memory material.
24 . The method of claim 23 wherein the shape memory material has a temperature transition between about 20° C. and about 40° C.
25 . The method of claim 23 wherein the shape memory material is selected from the group consisting of shape memory polymers and shape memory alloys.
26 . The method of claim 20 wherein the biocompatible substrate is selected from the group consisting of a foam, film, tissue scaffold, pledget, buttress, mesh and combinations thereof.
27 . The method of claim 20 wherein the biocompatible substrate comprises a surgical mesh.