Cholesteryl Sulfate-Containing Composition As A Haemostatic

1 - 30 . (canceled)

31 . A hemostatic agent comprising a cholesterol sulfate and a carrier material.

32 . The hemostatic agent of claim 31 , wherein the carrier material is hydrophilic.

33 . The hemostatic agent of claim 31 , wherein the carrier material is selected from the group consisting of natural polymers, synthetic polymers, and mixtures thereof.

34 . The hemostatic agent of claim 31 , wherein the carrier material is selected from the group consisting of polysaccharides, glucosaminoglycanes, proteins, synthetic polymers, and mixtures of the foregoing.

35 . The hemostatic agent of claim 31 , wherein the carrier material is collagen.

36 . The hemostatic agent of claim 31 , wherein the carrier material is a conventional wound dressing.

37 . The hemostatic agent of claim 31 , wherein the cholesterol sulfate is sodium cholesterol sulfate.

38 . The hemostatic agent of claim 31 , having a homogeneous distribution of the ingredients in the carrier material.

39 . The hemostatic agent of claim 31 , wherein the hemostatic agent comprises

at least 50% by wt of carrier material(s),

at least 0.03% by wt of cholesterol sulfate,

0 to 40% by wt of one or more further active agents

0 to 40% by wt of one or more auxiliary substances, and

less than 25% by wt of water,

in each case relative to the total quantity of the hemostatic agent.

40 . A composition comprising cholesterol sulfate and a carrier material, wherein a carrier material of a mixture of a cross-linked polymer and a non-gellable polysaccharide is excluded, and wherein the composition takes the shape of a layer.

41 . The composition of claim 40 , wherein the carrier material comprises at least one of natural polymers and synthetic polymers.

42 . The composition of claim 40 , wherein the carrier material is selected from the group consisting of freeze-dried collagen matrices, freeze-dried alginate matrices, freeze-dried hyaluronic acid matrices, freeze-dried chitosan matrices, freeze-dried collagen-alginate matrices, freeze-dried alginate-hyaluronic acid matrices, freeze-dried alginate-polyacrylic acid matrices or woven fleeces, compresses or gauzes.

43 . A method for preparing the hemostatic agent of claim 31 , the method comprising:

1. preparing an aqueous solution or suspension of at least one carrier material,

2. admixing of cholesterol sulfate and, optionally, one or more active agents and/or auxiliary substances,

3. pouring the mixture from step 2, and

4. drying the mixture.

44 . The method of claim 43 , wherein, in step 2, the cholesterol sulfate is admixed in the form of an aqueous vesicle solution.

45 . The method of claim 43 , wherein, in step 2, the cholesterol sulfate is admixed in the form of carrier particles coated with cholesterol sulfate.

46 . The method of claim 43 , wherein step 3 comprises pouring into a mold and step 4 comprises freezing the mixture in the mold and freeze-drying the mixture.

47 . A method for preparing a haemostatic by applying cholesterol sulfate onto a layer-like carrier material.

48 . The method of claim 47 , wherein the applying takes place by spray coating.

49 . The method of claim 47 , wherein the application takes place by steeping the carrier material in a cholesterol sulfate-containing solution and subsequent drying.

50 . The method of claim 47 , wherein the application takes place by steeping the carrier material in an aqueous vesicle solution of cholesterol sulfate.