Pyridinium boronic acid quenchers for use in analyte sensors
View Patent ↗Novel pyridinium salts functionalized with boronic acid and methods of making them are disclosed. When combined with a fluorescent dye, the compounds are useful in the detection of polyhydroxyl-substituted organic molecules.
1. The compound:
2. A method of making the compound of claim 1 , comprising the steps of:
3. The compound:
4. A method of making the compound of claim 3 , comprising the steps of:
5. A glucose sensor comprising the compound of claim 1 and a fluorescent dye.
6. The glucose sensor of claim 5 , wherein said compound is in the form of a polymer.
7. The glucose sensor of claim 5 , further comprising a glucose permeable immobilizing means.
8. The glucose sensor of claim 7 , wherein said glucose permeable immobilizing means is a polymer matrix or a semipermeable membrane.
9. A glucose sensor comprising the compound of claim 3 and a fluorescent dye.
10. The glucose sensor of claim 9 , wherein said compound is in the form of a polymer.
11. The glucose sensor of claim 9 , further comprising a glucose permeable immobilizing means.
12. The glucose sensor of claim 11 , wherein said glucose permeable immobilizing means is a polymer matrix or a semipermeable membrane.