ORAL COMPOSITION AND METHOD OF FORMING AND USING SAME
An oral composition for the treatment of dry mouth symptoms and other conditions, a method of forming the oral composition, and a method of using the oral composition are disclosed. The oral composition includes a plurality of enzymes to prevent formation of and/or facilitate the break up of biofilm in an oral cavity and a metal ion management system to inhibit growth of gram negative bacteria.
1 . An oral composition comprising:
a carrier comprising a solvent;
a plurality of enzymes selected from the group consisting of lysozyme, amylase, amyloglucosidase, glucosidase, peptizyme, and papain; and
a metal ion management formulation comprising one or more compounds selected from the group consisting of sodium EDTA, phytic acid, and lactoferrin.
2 . The oral composition of claim 1 , further comprising zinc gluconate.
3 . The oral composition of claim 1 , further comprising calcium lactate.
4 . The oral composition of claim 1 , wherein the solvent comprises purified water, propylene glycol, and sorbitol.
5 . The oral composition of claim 1 , wherein the carrier comprises a thickener selected from the group consisting of propanediol, carboxymethyl cellulose, cellulose gum, polyvinyl pyrolidone, hydroxylethyl cellulose, xanthum gum, and combinations thereof.
6 . The oral composition of claim 1 , wherein the carrier comprises a moisturizing agent.
7 . A method of treating dry mouth symptoms using the oral composition of claim 1 , the method comprising the steps of:
applying the composition of claim 1 to an oral cavity; and
discharging the composition.
8 . An oral composition, the composition comprising:
a carrier comprising a solvent;
zinc gluconate;
a plurality of enzymes selected from the group consisting of lysozyme, amylase, amyloglucosidase, glucosidase, peptizyme, and papain; and
a metal ion management formulation comprising one or more compounds selected from the group consisting of sodium EDTA, phytic acid, and lactoferrin.
9 . The oral composition of claim 8 , wherein the pH of the composition is between about 5 and about 5.5.
10 . The oral composition of claim 8 , wherein the specific gravity of the composition is between about 1.01 and about 1.04.
11 . The oral composition of claim 8 , wherein the solvent comprises purified water, propylene glycol, and sorbitol.
12 . The oral composition of claim 8 , wherein the plurality of enzymes comprises lysozyme, amylase, amyloglucosidase, glucosidase, peptizyme, and papain.
13 . The oral composition of claim 8 , wherein the metal ion management formulation comprises phytic acid and lactoferrin.
14 . The oral composition of claim 8 consisting essentially of:
one or more solvents;
a sweetener;
one or more preservatives;
a moisturizer;
an emulsifier;
the zinc gluconate;
one or more pH stabilizers;
the plurality of enzymes; and
the metal ion management formulation.
15 . A method of using the oral composition of claim 8 , the method comprising the steps of:
applying the composition of claim 8 to an oral cavity; and
discharging the composition.
16 . A composition for treatment of dry mouth symptoms, the composition comprising:
a carrier comprising a solvent;
zinc gluconate;
calcium lactate;
a plurality of enzymes selected from the group consisting of lysozyme, amylase, amyloglucosidase, glucosidase, peptizyme, and papain; and
a metal ion management formulation comprising one or more compounds selected from the group consisting of sodium EDTA, phytic acid, and lactoferrin.
17 . The composition for treatment of dry mouth symptoms of claim 16 , wherein the plurality of enzymes comprises lysozyme, amylase, amyloglucosidase, glucosidase, peptizyme, and papain.
18 . The composition for treatment of dry mouth symptoms of claim 16 , wherein the metal ion management formulation comprises lactoferrin.
19 . The composition for treatment of dry mouth symptoms of claim 16 , further comprising a moisturizing agent.
20 . A method of treating dry mouth symptoms using the composition for treatment of dry mouth symptoms of claim 16 , the method comprising the steps of:
applying the composition of claim 16 to an oral cavity; and
discharging the composition.