Antimicrobial hand wash
View Patent ↗An antimicrobial hand wash includes a soap, an antimicrobial agent, and an amine salt. The amine salt is found to increase the antimicrobial efficacy of the hand wash. The amine salt produced through the reaction of monoethanolamine and lactic acid is of particular interest as a soap addition. In processes of this invention, it is possible to create the desired amine salt in the soap in situ.
1. A process for preparing an antimicrobial hand wash comprising the steps of:
combining a fatty acid with a nitrogenous base to produce a soap and an excess of base;
neutralizing the excess base with a neutralizing acid selected from the group consisting of acetic acid, lactic acid, glycolic acid, acetylsalicylic acid, nicotinic acid, benzoic acid, isopropanoic acid, oxalic acid, succinic acid, benzoic acid anhydride, mixed phosphoanhydride, and mixtures thereof.
2. The process of claim 1 , wherein the fatty acid is selected from the group consisting of fatty acids derived from crude fats and carboxylic acids having from 6 to 40 carbon atoms in the main fatty chain.
3. The process of claim 1 , wherein the fatty acid is selected from the group consisting of arachidic acid, arachidonic acid, beeswax acid, behenic acid, capric acid, caproic acid, caprylic acid, C10-40 hydroxyalkyl acid, C32-36 isoalkyl acid, coconut acid, corn acid, cottonseed acid, erucic acid, hydrogenated coconut acid, hydrogenated menhaden acid, hydrogenated palm acid, hydrogenated tallow acid, hydroxystearic acid, isomerized linoleic acid, isomerized safflower acid, isostearic acid, lauric acid, linoleic acid, myristic acid, oleic acid, olive acid, palm acid, palmitic acid, palm kernel acid, peanut acid, pelargonic acid, rapeseed acid, rice bran acid, ricinoleic acid, safflower acid, soy acid, stearic acid, sunflower seed acid, tall oil acid, tallow acid, undecanoic acid, undecylenic acid, wheat germ acid, and mixtures thereof.
4. The process of claim 1 , wherein the nitrogenous base is selected from the group consisting of 2-aminobutanol, aminoethyl propanediol, aminomethyl propanol, aminopropanediol, bis-hydroxyethyl tromethamine, butyl diethanolamine, butylethanolamine, dibutyl ethanolamine, diethanolamine, diisopropanolamine, diisopropylamine, dimethyl isopropanolamine, monoethanolamine, dimethyl monoethanolamine, ethyl ethanolamine, isopropanolamine, isopropylamine, methylethanolamine, methylglucamine, morpholine, triethanolamine, triispropanolamine, tromethamine, and mixtures thereof.
5. The process of claim 1 , wherein the mole to mole ratio of the nitrogenous base to fatty acid is from about 1.5:1 to 3:1.
6. The process of claim 1 , further comprising the step of adding a phenol-based antimicrobial agent to the soap.
7. The process of claim 6 , wherein the antimicrobial agent is selected from the group consisting of triclosan,2,2′-dihydroxy-5,5′-dibromodiphenyl ether, p-chloro-m-xylenol, ortho-phenylphenol, and mixtures thereof.
8. The process of claim 1 , wherein the fatty acid is lauric acid, the nitrogenous base is monoethanolamine, and the neutralizing acid is lactic acid.