IP Library Granted Patent US 8,858,647
Granted Patent B2
US 8,858,647 · App. 13/101,022 · Granted Oct 14, 2014

Method and apparatus for a process creating an internal tissue graft for animal and human reconstructive purposes

Inventor: Barry Markman (Las Vegas, NV)
A61F2/02A61F2/062
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Quick Facts
Patent No.
US 8,858,647
App. No.
13/101,022
Granted
Oct 14, 2014
Kind
B2
Abstract

A method and apparatus is provided for creating an internal reconstruction tissue graft. Templates may be used to create a multitude of patterns in a variety of tissue reconstruction grafts. An apparatus may be used to create an internal tissue graft for reconstruction through either compression and/or removal of segments. An apparatus may be used, through either compression and or removal of segments of a preformed template made of synthetics and or metal that mirrors a template that can be used as an internal tissue graft for reconstruction. In a method, such as using software analysis and an apparatus, the physical properties of the tissue graft and its pre- and post-operative properties and appearance may be measured.

Claims (28)

1. A method for creating anatomically designed tissue reconstruction grafts comprising the steps of:

(a) collecting information regarding characteristics of an anatomical site of a human body at which an internal tissue graft is needed;

(b) determining desired characteristics of a reconstructive tissue graft from said collected information;

(c) creating a template, said template comprising a body which has a configuration which depends upon said collected information regarding characteristics of said anatomical site and is configured to aid in modifying a tissue graft to create a plurality of different surface patterns in a tissue graft for creating a reconstructive tissue graft having said desired characteristics;

(d) obtaining a tissue graft from a location different than said anatomical site;

(e) utilizing said template to create said reconstructive tissue graft by compressing, cutting or removing portions of said tissue graft to change a natural surface of a tissue graft to include a plurality of different surface patterns; and

(f) implanting said reconstructive tissue graft at said anatomical site.

2. The method according to claim 1 , wherein said tissue graft comprises human tissue.

3. The method according to claim 1 , wherein said tissue graft comprises cellular non human tissue, including cellular and acellular processed grafts.

4. The method according to claim 1 , wherein said tissue graft comprises one or more synthetic materials.

5. The method according to claim 1 , wherein at least one of said plurality of different surface patterns is configured to permit the egress of fluid from said site.

6. The method according to claim 1 , wherein said tissue graft has a thickness and wherein said plurality of different surface patterns may be either full thickness or partial thickness.

7. The method according to claim 1 , wherein said tissue graft has an anterior surface and a posterior surface and said plurality of surface patterns are associated with both said anterior and posterior surfaces.

8. The method according to claim 1 , wherein at least one of said plurality of different surface patterns is configured to permit controlled expansion of said reconstructive tissue graft.

9. The method according to claim 1 , wherein at least one of said plurality of different surface patterns is configured to provide enhanced stress relief during motion of and reduction of internal pressure on the reconstructive tissue graft when implanted at said site.

10. The method according to claim 1 , wherein at least one of said plurality of different surface patterns is configured to provide enhanced adhesion between the reconstructive tissue graft and tissue at said anatomical site.

11. The method according to claim 1 , wherein at least one of said plurality of different surface patterns is configured to provide enhanced retention of various medicants and materials.

12. The method according to claim 1 , wherein said step of utilizing said template comprises compressing said tissue graft against a surface of said template to create one or more of said plurality of different surface patterns.

13. The method according to claim 1 wherein one or more of said plurality of different surface patterns comprise variegations.

14. A method for creating anatomically designed tissue reconstruction grafts comprising the steps of:

(a) collecting information regarding characteristics of an anatomical site of a human body at which an internal tissue graft is needed;

(b) determining desired characteristics of a reconstructive tissue graft from said collected information;

(c) obtaining a tissue graft from a location different than said anatomical site;

(d) utilizing an apparatus having a configuration which is dependent upon said desired characteristics to compress, cut or remove portions of said tissue graft to change a natural surface of said tissue graft to create a reconstructive tissue graft having a plurality of different surface patterns, said surface patterns designed to control expansion of said reconstructive tissue graft when said reconstructive tissue graft is implanted at said anatomical site, increase adhesion between said reconstructive tissue graft and said anatomical site when the reconstructive tissue graft is implanted at said anatomical site, and enhance retention of medicants and materials at said anatomical site when said reconstructive tissue graft is implanted at said anatomical site; and

(e) implanting said reconstructive tissue graft at said anatomical site.

15. The method according to claim 14 , wherein said tissue graft comprises human tissue.

16. The method according to claim 14 , wherein said tissue graft comprises cellular non human tissue, including cellular and acellular processed grafts.

17. The method according to claim 14 , wherein said tissue graft comprises one or more synthetic materials.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF APPLICANT PREVIOUSLY RECORDED ON REEL 67051 FRAME 308. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jul 16, 2025
From: MARKMAN BIOLOGICS CORPORATION
To: CELLTHERX CORP
Reel/Frame 072050/0092 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 9, 2024
From: MARKMAN BIOLOGICS CORPORATION
To: CELLTHERX
Reel/Frame 067051/0308 →
RELEASE OF SECURITY INTEREST Recorded Apr 8, 2024
From: MARKMAN, BARRY
To: MARKMAN BIOLOGICS CORPORATION
Reel/Frame 067032/0745 →
SECURITY INTEREST Recorded Aug 28, 2020
From: MARKMAN BIOLOGICS CORPORATION
To: MARKMAN, BARRY
Reel/Frame 053627/0532 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2019
From: MARKMAN, BARRY
To: MARKMAN BIOLOGICS CORPORATION
Reel/Frame 048466/0528 →
Continuity (2)
Provisional Application 61331805 · May 5, 2010
Related Publication 20110276039A1 · Nov 10, 2011