VASO-OCCLUSIVE DEVICES WITH ATTACHED POLYMER STRUCTURES
Disclosed herein are vaso-occlusive devices for forming occluding the vasculature of a patient. More particularly, disclosed herein are vaso-occlusive devices comprising at least one polymer structure and methods of making and using these devices.
1 . A vaso-occlusive device comprising a core element having an outer surface and a polymer structure surrounding a substantial portion of the outer surface of the core element, wherein the polymer structure is a multi-layered polymeric structure, comprising an inner polymer member and an outer polymer member, wherein the outer polymer member covers the inner polymer member.
2 . The vaso-occlusive device of claim 1 , wherein the polymer structure is shaped into a tubular sheath.
3 . The vaso-occlusive device of claim 1 , wherein the inner polymer member comprises monofilaments or multi-filaments.
4 . The vaso-occlusive device of claim 3 , wherein the inner polymer member is wound into a helical shape.
5 . The device of claim 1 , wherein the outer polymer member comprises monofilaments or multi-filaments.
6 . The device of claim 5 , wherein the outer polymer member is braided into a tubular shape.
7 . The vaso-occlusive device of claim 1 , wherein the inner polymer member comprises a closed pitch coil and the outer polymer member comprises a braided tubular structure.
8 . The vaso-occlusive device of claim 1 , wherein the polymer structure comprises one or more biodegradable polymers.
9 . The vaso-occlusive device of claim 8 , wherein the biodegradable polymers comprises at least one polymer selected form group consisting of: lactide, glycolide, trimethylene carbonate and caprolactone polymers and their copolymers; hydroxybutyrate and polyhydroxyvalerate and their block and random copolymers; a polyether ester; anhydrides, polymers and copolymers of sebacic acid, hexadecandioic acid; and orthoesters.
10 . The vaso-occlusive device of claim 1 , where the polymer structure comprises one or more non-biodegradable polymers.
11 . The vaso-occlusive device of claim 10 , wherein the non-biodegradable polymers comprises at least one polymer selected from the group consisting of polyethylene teraphthalate, polytetraflouroethylene, polyurethane, polypropylene and Nylon materials.
12 . The vaso-occlusive device of claim 1 , where the polymer structure comprises one or more non-biodegradable polymers and one or more biodegradable polymers.
13 . The vaso-occlusive device of claim 1 , wherein the inner polymer member comprises a biodegradable polymer and the outer polymer member comprises a non-biodegradable polymer.
14 . The vaso-occlusive device of claim 1 , wherein the outer non-biodegradable polymer member comprises openings which allow the inner biodegradable polymer member to biodegrade through the openings.
15 . The vaso-occlusive device of claim 1 , wherein the core element comprises a wire formed into a helically wound primary shape.
16 . The vaso-occlusive device of claim 15 , where the core element has a secondary shape that self-forms upon deployment.
17 . The vaso-occlusive device of claim 16 , where the secondary shape is selected from the group consisting of cloverleaf shaped, helically-shaped, figure-8 shaped, flower-shaped, vortex-shaped, ovoid, randomly shaped, and substantially spherical.
18 . The vaso-occlusive device of claim 16 , wherein the secondary shape comprises a series of conjoined helical segments.
19 . The vaso-occlusive device of claim 18 , wherein at least two of the conjoined helical segments have differing diameters or differing orientation axes.
20 . The vaso-occlusive device of claim 1 , further comprising a detachment junction.
21 . A method of at least partially occluding an aneurysm, the method comprising introducing a vaso-occlusive device according to claim 1 into the aneurysm.