Antiviral treatments
View Patent ↗The invention provides unit dosage forms, kits, and methods useful for treating viral infections.
1. A method for treating a viral infection in a human in need thereof comprising administering in a single intravenous administration an effective anti-viral amount of a compound of formula I:
or a pharmaceutically acceptable salt thereof, to the human, wherein the viral infection is an H3N2, H1N1, H5N1, avian, or seasonal influenza infection.
2. The method of claim 1 , wherein the compound of formula I is a compound of formula Ia:
or a pharmaceutically acceptable salt thereof.
3. The method of claim 1 , wherein the effective anti-viral amount is up to about 800 mg.
4. The method of claim 3 , wherein the effective anti-viral amount is up to about 600 mg.
5. The method of claim 4 , wherein the effective anti-viral amount is up to about 300 mg.
6. The method of claim 1 , wherein the effective anti-viral amount is about 600 mg.
7. The method of claim 1 , wherein the effective anti-viral amount is about 300 mg.
8. The method of claim 1 , wherein the plasma concentration of the compound is higher than the IC 50 of the virus causing the viral infection 12 hours following administration of the compound.