IP Library Granted Patent US 8,905,930
Granted Patent B2
US 8,905,930 · App. 13/112,504 · Granted Dec 9, 2014

Infusion pressure control using blood pressure

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Quick Facts
Patent No.
US 8,905,930
App. No.
13/112,504
Granted
Dec 9, 2014
Kind
B2
Abstract

Methods, systems, and software for controlling infusion pressure, such as during a medical procedure, using systemic blood pressure are described. Systemic blood pressure, such as brachial arm blood pressure or radial artery blood pressure, may be used to estimate central retinal artery blood pressure to estimate critical closing pressure. Further, the disclosure relates to controlling infusion pressure to prevent an increase in intraocular pressure above the estimated critical closing pressure when such is not desired, and, when such is desired, using systemic blood pressure and infusion pressure to control an intentional increase in intraocular pressure above the estimated critical closing pressure to stop intraocular bleeding.

Claims (31)

1. A method for controlling infusion pressure during an intraocular surgical procedure, the method comprising:

determining an infusion pressure of a patient's eye with a first pressure determining device;

determining a blood pressure indicative of a patient's central retinal artery blood pressure with a second pressure determining device;

determining, with a processor, an estimated critical closing pressure of a central retinal artery of the eye based on the blood pressure indicative of a patient's central retinal artery blood pressure;

comparing, with the processor, the infusion pressure to the estimated critical closing pressure; and

triggering an alarm when the infusion pressure reaches a selected pressure relative to the estimated critical closing pressure,

wherein determining a blood pressure indicative of a patient's central retinal artery blood pressure with a second pressure determining device comprises:

determining a patient's systemic blood pressure with the second pressure determining device; and

converting the systemic blood pressure into an estimated central retinal artery blood pressure with the processor.

2. The method of claim 1 , wherein determining a patient's systemic blood pressure with the second pressure determining device comprises determining at least one of the patient's brachial artery blood pressure or radial artery blood pressure with the second pressure determining device.

3. The method of claim 1 , wherein converting the systemic blood pressure into the estimated central retinal artery blood pressure with the processor comprises converting, with the processor, the systemic blood pressure into the estimated central retinal artery blood pressure using an ophthalmodynamometry offset.

4. The method of claim 1 , wherein triggering an alarm when the infusion pressure reaches a selected pressure relative to the estimated critical closing pressure comprises triggering at least one of a visual or audible alarm.

5. The method of claim 1 further comprising automatically adjusting infusion pressure when the infusion pressure is at a selected value relative to the estimated critical closing pressure.

6. The method of claim 5 , wherein automatically adjusting infusion pressure when the infusion pressure is at a selected value relative to the estimated critical closing pressure comprises automatically reducing infusion pressure when the infusion pressure is equal to or greater than the selected pressure and wherein the selected pressure is the estimated critical closing pressure.

7. A non-transitory computer program product for controlling infusion pressure, the computer program product comprising machine-readable instructions embodied on tangible media operable when executed to:

read an infusion pressure of a patient's eye;

determine an estimate of a patient's central retinal artery blood pressure;

determine an estimated critical closing pressure of a central retinal artery of the eye based on the estimated central retinal artery blood pressure; and

trigger an alarm when the infusion pressure reaches a selected pressure relative to the estimated critical closing pressure comprises machine-readable instructions operable when executed to trigger at least one of a visual or audible alarm.

8. The computer program product of claim 7 , wherein the machine-readable instructions operable when executed to determine an estimate of a patient's central retinal artery blood pressure comprises machine-readable instructions operable when executed to:

read a patient's systemic blood pressure; and

convert the systemic blood pressure into the estimated central retinal artery blood pressure.

9. The computer program product of claim 8 , wherein the machine-readable instructions operable when executed to read a patient's systemic blood pressure comprises machine-readable instructions operable when executed to read at least one of the patient's brachial artery blood pressure or radial artery blood pressure.

10. The computer program product of claim 7 , wherein the machine-readable instructions operable when executed to convert the systemic blood pressure into the estimated central retinal artery blood pressure comprises machine-readable instructions operable when executed to convert the systemic blood pressure into the estimated central retinal artery blood pressure with an ophthalmodynamometry offset.

11. The computer program product of claim 7 further comprising machine-readable instructions operable when executed to trigger an alarm when the infusion pressure reaches a selected pressure relative to the estimated critical closing pressure.

12. A non-transitory computer program product for controlling infusion pressure, the computer program product comprising machine-readable instructions embodied on tangible media operable when executed to:

read an infusion pressure of a patient's eye;

determine an estimate of a patient's central retinal artery blood pressure;

determine an estimated critical closing pressure of a central retinal artery of the eye based on the estimated central retinal artery blood pressure; and

automatically adjust infusion pressure when the infusion pressure is at a selected value relative to the estimated critical closing pressure.

13. The computer program product of claim 12 , wherein the machine readable instructions operable when executed to automatically adjust infusion pressure when the infusion pressure is at a selected value relative to the estimated critical closing pressure comprises machine readable instructions operable when executed to automatically reduce infusion pressure when the infusion pressure is equal to or greater than the selected pressure and wherein the selected pressure is the estimated critical closing pressure.

Assignments (4)
CONFIRMATORY DEED OF ASSIGNMENT EFFECTIVE APRIL 8, 2019 Recorded Dec 10, 2019
From: NOVARTIS AG
To: ALCON INC.
Reel/Frame 051454/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 4, 2018
From: ALCON RESEARCH, LTD.
To: NOVARTIS AG
Reel/Frame 047669/0091 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 25, 2017
From: CHARLES, STEVEN T.
To: ALCON RESEARCH LTD
Reel/Frame 042136/0850 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 25, 2017
From: ALCON RESEARCH LTD.
To: NOVARTIS AG
Reel/Frame 042137/0145 →