IP Library › Granted Patent US 8,697,130
Granted Patent B1
US 8,697,130 · App. 13/114,076 · Granted Apr 15, 2014

Non-irritating benzoyl peroxide

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Quick Facts
Patent No.
US 8,697,130
App. No.
13/114,076
Granted
Apr 15, 2014
Kind
B1
Abstract

Crystalline benzoyl peroxide particles having a particle size no greater than 25 microns and formed by wet milling in the absence of solvents and wherein the crystalline benzoyl peroxide is not irritating to the skin. A therapeutic or cosmetic composition comprising a water-based gel containing the crystalline benzoyl peroxide.

Claims (14)

1. Crystalline, solvent-free, benzoyl peroxide particles having a particle size no greater than 25 microns and formed by wet milling benzoyl peroxide consisting of solid benzoyl peroxide, in the absence of solvents; wherein the crystalline benzoyl peroxide is non-irritating to the skin.

2. The benzoyl peroxide particles of claim 1 wherein the particle size is not greater than 10 microns.

3. The benzoyl peroxide particles of claim 1 wherein at least 90% of the particles are less than 3.5 microns in size.

4. The benzoyl peroxide particles of claim 1 wherein at least 95% of the particles are less than 3.5 microns in size.

5. The benzoyl peroxide particles of claim 1 wherein an average particle size is from 1 to 2 microns.

6. A therapeutic or cosmetic composition comprising a water-based gel comprising crystalline, solvent-free, benzoyl peroxide particles having a particle size no greater than 25 microns, and formed by wet milling benzoyl peroxide consisting of solid benzoyl peroxide, in the absence of solvents; wherein the crystalline benzoyl peroxide is non-irritating to the skin.

7. The composition of claim 6 wherein the particle size is not greater than 10 microns.

8. The composition of claim 6 wherein at least 90% of the particles are less than 3.5 microns in size.

9. The composition of claim 6 wherein at least 95% of the particles are less than 3.5 microns in size.

10. The composition of claim 6 wherein an average particle size is from 1 to 2 microns.

11. The composition of claim 6 further comprising a dispersing system.

12. The composition of claim 11 wherein the dispersion system comprises at least one selected from the group consisting of suspending agents, gelling aids, buffering agents, and dispersants.

13. The composition of claim 11 wherein the composition contains about 25 to 65% by weight benzoyl peroxide.

14. A method for treating skin lesions in a patient that exhibits acute sensitivity to benzoyl peroxide which comprises applying to the lesions a therapeutic or cosmetic composition according to claim 6 in a pharmaceutically acceptable vehicle.

Assignments (8)
PATENT SECURITY AGREEMENT Recorded Sep 4, 2025
From: VANTAGE SPECIALTIES, INC.; VANTAGE SPECIALTY CHEMICALS, INC.; VANTAGE SPECIALTY INGREDIENTS, INC.
To: APOLLO ADMINISTRATIVE AGENCY LLC, AS ADMINISTRATIVE AGENT AND COLLATERAL AGENT
Reel/Frame 072801/0720 →
TERMINATION AND RELEASE OF FIRST LIEN SECURITY INTEREST IN PATENTS RECORDED AT REEL 044700, FRAME 0728 Recorded Aug 29, 2025
From: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
To: VANTAGE SPECIALTIES, INC.; VANTAGE SPECIALTY INGREDIENTS, INC.
Reel/Frame 072759/0388 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN SECOND LIEN PATENT SECURITY AGREEMENT RECORDED AT REEL 044700, FRAME 0582 Recorded Mar 14, 2023
From: MORGAN STANLEY SENIOR FUNDING, INC. AS COLLATERAL AGENT
To: VANTAGE SPECIALTIES, INC.; VANTAGE SPECIALITY INGREDIENTS, INC.
Reel/Frame 063084/0479 →
FIRST LIEN PATENT SECURITY AGREEMENT Recorded Dec 5, 2017
From: VANTAGE SPECIALTIES, INC.; VANTAGE SPECIALTY INGREDIENTS, INC.
To: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
Reel/Frame 044700/0728 →
SECOND LIEN PATENT SECURITY AGREEMENT Recorded Dec 5, 2017
From: VANTAGE SPECIALTIES, INC.; VANTAGE SPECIALTY INGREDIENTS, INC.
To: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
Reel/Frame 044700/0582 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 24, 2015
From: ESSENTIAL INGREDIENTS, INC.
To: VANTAGE SPECIALTY INGREDIENTS, INC.
Reel/Frame 037129/0982 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 1, 2015
From: ESSENTIAL INGREDIENTS, INC.
To: VANTAGE SPECIALTY INGREDIENTS, INC.
Reel/Frame 035949/0943 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 1, 2012
From: GERLACH, CHRIS; DAVIES, MIKE
To: ESSENTIAL INGREDIENTS, INC.
Reel/Frame 028134/0570 →