IP Library Patent Application 13120765
Patent Application
App. No. 13/120,765

HERBAL COMPOSITION AND METHOD FOR THE TREATMENT OF VIRAL INFECTION

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Patent No.
US None
App. No.
13/120,765
Abstract

The present invention relates to a herbal composition comprising extract of the plant Indigofera heterantha. The invention also relates to a process for the preparation of the herbal composition. The invention further relates to the use of the herbal composition for the treatment of viral infection, particularly caused by herpes simplex viruses.

Claims (20)

1 - 21 . (canceled)

22 . An isolated extract from roots of the plant Indigofera heterantha prepared by stirring the roots of the plant in a solvent in a ratio of 1:5 to 1:40 weight/volume for 2 hours to 24 hours at 40° C. to 50° C.; concentrating the extract; and optionally enriching the extract by solvent partitioning or chromatography.

23 . A herbal composition comprising a therapeutically effective amount of an isolated extract of roots of the plant Indigofera heterantha, prepared according to claim 22 , either alone or in combination with a pharmaceutically acceptable carrier.

24 . A process for the preparation of the herbal composition as claimed in claim 23 , comprising:

(a) preparing an extract from the roots of the plant Indigofera heterantha by stirring in a solvent in a ratio of 1:5 to 1:40 weight/volume for 2 hours to 24 hours at 40° C. to 50° C.;

(b) concentrating the solvent extract obtained in step (a);

(c) optionally drying the extract obtained in step (b) under high vacuum (0.01-5 mm Hg);

(d) optionally enriching the extract obtained in step (b) or step (c) using materials selected from polyamide resin, gelatin/sodium chloride solution, polyvinylpyrrolidone, caffeine, lead (II) acetate or hide powder;

(e) optionally enriching the extract obtained in step (b), step (c) or step (d) by solvent partitioning or chromatography; and

(f) optionally mixing the extract of step (b), step (c), step (d) or step(c) with a pharmaceutically acceptable carrier.

25 . The process as claimed in claim 24 , wherein the solvent for extracting the plant Indigofera heterantha is selected from methanol, ethanol, n-propanol, isopropanol, n-butanol, acetone, ethyl acetate, dichloromethane, water, and a mixture thereof.

26 . The process as claimed in claim 25 , wherein the solvent for extracting the plant Indigofera heterantha is a mixture of methanol and water, or ethanol and water.

27 . The process as claimed in claim 24 , wherein the material used for enriching the extract is polyamide resin.

28 . The process as claimed in claim 24 , wherein the solvents for enriching the extract by solvent partitioning arc selected from water, petroleum ether, dichloromethane, chloroform, ethyl acetate, methanol, acetone, acetonitrile, n-propanol, iso-propanol, and butanol or a mixture thereof.

29 . The herbal composition as claimed in claim 23 , wherein the herbal composition is formulated for oral or topical administration.

30 . The herbal composition as claimed in claim 29 , wherein the herbal composition is formulated for topical administration in the form of a cream, gel or ointment.

31 . The herbal composition as claimed in claim 30 , wherein the herbal composition comprises 5% to 50% (w/w) of the extract.

32 . A method of treating viral infection comprising administering to a subject in need thereof, a herbal composition as claimed in claim 23 .

33 . The method as claimed in claim 32 , wherein the viral infection is caused by HSV.

34 . The method as claimed in claim 33 , wherein the viral infection is caused by HSV-2.

Assignments (3)
CHANGE OF NAME Recorded Nov 21, 2012
From: PIRAMAL HEALTHCARE LIMITED
To: PIRAMAL ENTERPRISES LIMITED
Reel/Frame 029337/0729 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 20, 2012
From: PIRAMAL LIFE SCIENCES LIMITED
To: PIRAMAL HEALTHCARE LIMITED
Reel/Frame 028599/0103 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 1, 2011
From: THOMAS, BECKY MARY; SHANMUGAM, SARAVANABALAJI; SAKLANI, ARVIND; GODBOLE, SHREEKANT NAGESH; NAIK, VINAYAK RAGHOBA; MISHRA, PRABHU DUTT; HARIHARAN, SIVARAMAKRISHNAN; ENOSE, ARNO APPAVOO; KAUSHIK, RITU
To: PIRAMAL LIFE SCIENCES LTD
Reel/Frame 026537/0872 →