Infusion of drugs
View Patent ↗An at least partly implantable system for injecting a substance into a patient's body, in particular a penis erection stimulation system comprises one or more infusion needles disposed within and implanted along with one or more housings adjacent the patient's left and right corpora cavernosa. A reservoir and a pump are also implanted inside the patient's body to supply the infusion needle with infusion liquid. A drive unit also adapted for implantation inside the patient's body is arranged for advancing and retracting the tip end of the infusion needle such that it penetrates the housing in at least one penetration area, preferably in two different penetration areas either simultaneously or in immediate time succession, thereby injecting drugs along with the infusion liquid into the patient's body for stimulating penis erection. The drive unit is provided for implantation remote from the injection area and comprises a mechanical drive element for transmitting kinetic energy from a remote location within the patient's body to the at least one infusion needle.
1. An at least partly implantable system for injecting a substance into a patient's body, comprising
at least one infusion needle disposed at least partly within at least one first housing with a tip end of the at least one infusion needle arranged for penetrating the at least one first housing's outer wall in at least one penetration area, the at least one first housing being adapted for implantation inside the patient's body, and
at least one drive unit adapted for implantation inside the patient's body, the at least one drive unit being coupled to the at least one infusion needle and arranged at least for advancing and retracting the tip end of the at least one infusion needle so that the at least one infusion needle penetrates, upon advancement of the tip end or ends thereof, said at least one penetration area so as to allow for injecting the substance through said at least one penetration area via the at least one infusion needle,
at least one reservoir adapted for implantation inside the patient's body in fluid connection with the at least one infusion needle to supply to the infusion needle the substance to be injected into the patient's body,
at least one second housing, wherein the at least one drive unit comprises a mechanical drive element for transmitting kinetic energy from a second housing having a remote location within the patient's body to the at least one infusion needle, the second housing is adapted for implantation inside the patient's body,
wherein the mechanical drive element comprises at least one of; at least one wire and at least one rotating shaft, directly or indirectly cooperating with the infusion needle so as to cause movement of the needle upon actuation of the wire.
2. The system of claim 1 , wherein the rotating shaft is at least one of; in the form of a worm screw and flexibly bendable.
3. The system of claim 1 , wherein at least one of the at least one wire and at least one rotating shaft extends through a conduit connecting the at least one infusion needle with a reservoir.
4. The system of claim 1 , wherein at least one of; pulling at least one of the at least one wire and turning the rotating shaft about its rotating axis, causes the tip end of the at least one infusion needle to displace laterally from a first to a second penetration area, or from a first penetration site to a second penetration site within a single penetration area, or laterally from a first to a second penetration area and from a first penetration site to a second penetration site within a single penetration area.
5. The system of claim 1 , wherein turning the rotating shaft about its axis of rotation, pulling at least one of the at least one wire, or turning the rotating shaft about its axis of rotation and pulling at least one of the pulling wires, causes the infusion needle to advance and/or retract.
6. The system of claim 1 , wherein at least two, preferably three, pulling wires are provided and arranged for allowing a two-dimensional lateral displacement of the tip end of the infusion needle.
7. The system of claim 1 , wherein the at least one drive unit further comprises as a drive at least one electric motor inside the housing accommodating the at least one infusion needle.
8. The system of claim 7 , further comprising wiring for transmitting electric energy from a remote location within the patient's body to the at least one motor.
9. The system of claim 8 , wherein the wiring is guided through a conduit connecting the at least one infusion needle with a reservoir.
10. The system of claim 1 , wherein the mechanical drive element of the at least one drive unit is arranged for advancing and/or retracting the tip end of the infusion needle.
11. The system of claim 1 , wherein the mechanical drive element of the at least one drive unit is arranged for displacing the tip end of the infusion needle in at least one lateral direction.
12. The system of claim 11 , wherein the mechanical drive element of the at least one drive unit is arranged for displacing the tip end of the infusion needle in two or more lateral directions.
13. The system of claim 11 , wherein the mechanical drive element of the at least one drive unit is arranged for displacing the tip end of the infusion needle in at least one lateral direction and for advancing and retracting the infusion needle.
14. The system of claim 11 , wherein the mechanical drive element of the at least one drive unit is arranged for displacing the tip end of the infusion needle in two or more lateral directions and for advancing and retracting the infusion needle.
15. The system of claim 1 , wherein the at least one infusion needle is arranged for penetrating the at least one housing's outer wall in at least two different penetration areas.
16. The system of claim 1 , wherein the at least one infusion needle has a tube-like body closed at the tip end and having a laterally arranged delivery exit port, wherein at least in the penetration area or areas the outer wall is made from a material which is self-sealing in respect of penetrations resulting from said at least one infusion needle.
17. The system of claim 1 , wherein the at least one infusion needle is flexibly bendable, wherein the tip end of each of the at least one infusion needle is arranged for penetrating the outer wall of a first housing and the other end thereof is arranged in a second housing for remote implantation inside the patient's body, the injection needle being sufficiently long to bridge the distance from the second housing for remote implantation to the first housing and further through the first housing up to the outer wall of the first housing.
18. The system of claim 1 , wherein the drive unit is configured to laterally displace the tip end of one infusion needle between two lateral positions such that the one infusion needle can penetrate the housing's outer wall in at least two different penetration areas, wherein the drive unit is configured to displace the tip end of the one infusion needle in at least one of; laterally to different penetration sites within each of said different penetration areas and at least two different lateral directions.
19. The system of claim 1 , wherein the reservoir comprises at least one first compartment accommodating or adapted to accommodate a first substance and at least one second compartment accommodating or adapted to accommodate a second substance, further comprising a mixing chamber for mixing the substance from the at least one first compartment with the substance from one or more of the at least one second compartment, wherein the substance contained in the at least one second compartment is in at least one of; powder form and freeze-dried form.
20. The system of claim 1 , further comprising at least one of at least one pump adapted for implantation inside the patient's body to advance the substance from the reservoir to the at least one infusion device, and an actuating means for direct manual operation of a pump and/or the drive unit.
21. The system of claim 1 , wherein at least one of; at least one motor is provided for actuating at least one of a pump, the drive unit and any other implantable energy consuming part of the system.
22. The system of claim 1 , comprising at least one of a pump, a drive unit, and a motor, further comprising an energy source for providing energy to at least one of the pump, the drive unit and the motor, and any other energy consuming part of the system, wherein the system comprises coupling elements for wireless energy transfer from outside the patient's body to the energy storage means for charging the energy storage means from outside a patient's body, when the energy storage means is implanted in a patient's body, wherein at least one feedback sensor is provided and adapted to sense one or more physical parameters of the patient and/or process parameters of the system, further comprising a feedback subsystem adapted to wirelessly send feedback information relating to the energy to be stored in the energy storage means from inside the human body to the outside thereof, wherein the system is adapted to use the feedback information for adjusting the amount of wireless energy transmitted by the energy transmitter and/or adapted to provide feedback on parameters relevant for the treatment, including the one or more physical parameters of the patient and/or the process parameters of the system.
23. The system of claim 22 , wherein the feedback information relates to an energy balance which is defined as at least one of; the balance between an amount of wireless energy received inside the human body and an amount of energy consumed by the at least one energy consuming part and a rate of wireless energy received inside the human body and a rate of energy consumed by the at least one energy consuming part.