Surface-treated calcium phosphate particles suitable for oral care and dental compositions
View Patent ↗Calcium phosphate particles are described comprising a surface treatment wherein the surface treatment comprises at least one sugar alcohol, at least one glycerophosphoric acid compound, or mixture thereof. Also described are various oral care compositions comprising surface treated calcium phosphate particles and methods of surface treating calcium phosphate particles.
1. Surface treated tricalcium phosphate particles, wherein the surface of the tricalcium phosphate particles comprise at least 0.05% by weight of at least one sugar alcohol, at least one glycerophosphoric acid compound, or mixture thereof, and wherein the surface treated tricalcium phosphate particles are in a dry powder form.
2. The surface treated tricalcium phosphate particles of claim 1 wherein the sugar alcohol has the general formula HOCH 2 [CH(OH)] n CH 2 OH, wherein n ranges from 4 to 6.
3. The surface treated tricalcium phosphate particles of claim 2 wherein the sugar alcohol is xylitol.
4. The surface treated tricalcium phosphate particles of claim 1 wherein glycerophosphoric acid compound is a salt having the general formula HO(CH) 2 (O)P(O)(O − )(M +n ) 2/n wherein M is H or a metal ion having a valency of n, or a hydrate thereof.
5. The surface treated tricalcium phosphate particles of claim 4 wherein the glycerophosphoric acid compound is sodium glycerophosphate, calcium glycerophosphate, or a mixture thereof.
6. The surface treated tricalcium phosphate particles of claim 1 wherein the concentration of surface treatment on the calcium phosphate particles ranges from about 0.1 wt-% to 10 wt-%.
7. An oral care composition prepared by a method comprising combining the surface treated tricalcium phosphate particles according to claim 1 with a fluoride-providing agent.
8. The oral care composition of claim 7 wherein the concentration of tricalcium phosphate ranges from 0.02 wt-% to 40 wt-% of the total solids content of the oral care composition.
9. A hardenable dental composition prepared by a method comprising combining a hardenable material and the surface treated tricalcium phosphate particles according to claim 1 .
10. A composition comprising:
the surface treated tricalcium phosphate particles according to claim 1 ; and
a fluoride-providing agent.
11. An oral care composition prepared by a method comprising combining the surface treated tricalcium phosphate particles according to claim 1 with one or more additional components of the oral care composition.