IP Library Granted Patent US 8,765,442
Granted Patent B2
US 8,765,442 · App. 13/140,279 · Granted Jul 1, 2014

Process for production of an enzyme product

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Quick Facts
Patent No.
US 8,765,442
App. No.
13/140,279
Granted
Jul 1, 2014
Kind
B2
Abstract

The invention relates to a process for production of an enzyme product having a plurality of enzyme activities obtained by fermentation of an Aspergillus strain.

Claims (33)

1. A process for the production of an enzyme composition, the process comprising the steps of submerged fermentation of an Aspergillus tubingensis strain having the deposit accession number CBS123488 in a fermentation medium, wherein said medium comprises sugar beet pulp and/or cereal bran to obtain a fermentation broth, and recovery of said enzyme composition from said fermentation medium, wherein said enzyme composition comprises

i. endo-polygalacturonase,

ii. exo-polygalacturonase,

iii. pectinesterase,

iv. pectin lyase,

v. cellulase,

vi. xylanase, and

vii. arabinanase.

2. The process according to claim 1 , wherein the fermentation medium comprises sugar beet pulp in the range of 1-30% w/w.

3. The process according to claim 1 , wherein the fermentation medium comprises sugar beet pulp in the range of 2-8% w/w.

4. The process according to claim 1 , wherein the fermentation medium comprises sugar beet pulp in the range of 3-7% w/w.

5. The process according to claim 1 , wherein the sugar beet pulp has a sugar content of 0.5-20% w/w.

6. The process according to claim 1 , wherein the sugar beet pulp has a sugar content of 2-8% w/w.

7. The process according to claim 1 , wherein the sugar beet pulp has a sugar content of 5-40% w/w.

8. The process according to claim 1 , wherein the sugar beet pulp is un-molassed.

9. The process according to claim 1 , wherein the cereal bran is wheat bran.

10. The process according to claim 9 , wherein the wheat bran has an arabinan content of 2-20% w/w.

11. The process according to claim 1 , wherein the Aspergillus tubingensis strain has not been genetically modified (non-GMO).

12. The process according to claim 1 , wherein the pH during the fermentation is in the range of 3-4.5.

13. The process according to claim 1 , wherein the pH during the fermentation is in the range of 3-4.

14. The process according to claim 1 , wherein the pH during the fermentation is in the range of 3.2-3.7.

15. The process according to claim 1 , wherein the temperature during the fermentation is in the range of 25-40° C.

16. The process according to claim 1 , wherein the temperature during the fermentation is in the range of 28-34° C.

17. The process according to claim 1 , wherein the fermentation is conducted as an aerobic fermentation.

18. The process according to claim 1 , wherein the fermentation medium further comprises ammonium sulphate and/or potassium nitrate.

19. The process according to claim 1 , wherein the fermentation comprises the steps of:

a. growing said Aspergillus tubingensis strain in an inoculum medium to obtain an inoculum, and

b. adding said inoculum to said fermentation medium.

20. The process according to claim 19 , wherein the inoculum medium comprises cereal bran and/or sugar beet pulp.

21. The process according to claim 19 , wherein the inoculum medium comprises wheat bran.

22. An enzyme product obtainable by a process according to claim 1 .

23. An enzyme product preparation comprising an enzyme product according to claim 22 , and an enzyme carrier.

24. The process of claim 1 , wherein said enzyme product is recovered in the form of a cell free broth from said fermentation broth.

Assignments (2)
CHANGE OF NAME Recorded Aug 19, 2013
From: DANISCO A/S
To: DUPONT NUTRITION BIOSCIENCES APS
Reel/Frame 031035/0589 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2011
From: GRONFELDT, METTE ZACHO
To: DANISCO A/S
Reel/Frame 027182/0341 →