FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF
Fluorinated compounds and methods of making fluorinated compounds are described herein.
1 . A fluorinated compound selected from the following: a fluorinated venlafaxine, a fluorinated duloxetine, a fluorinated varenicline, a fluorinated atomoxetine, a fluorinated sertraline, a fluorinated trazodone, a fluorinated mirtazapine, a fluorinated amitriptyline, a fluorinated amoxapine, a fluorinated clomipramine, a fluorinated imipramine, a fluorinated nortriptyline, a fluorinated trimipramine, a fluorinated maprotiline, a fluorinated nefazodone, a fluorinated sibutramine, a fluorinated fluoxetine, a fluorinated doxepin and a fluorinated lofepramine.
2 . The compound of claim 1 , wherein the compound is a fluorinated duloxetine.
3 . The compound of claim 1 , wherein the compound is a fluorinated varenicline.
4 . The compound of claim 1 , wherein the compound is a fluorinated atomoxetine.
5 . The compound of claim 1 , wherein the compound is a fluorinated sertraline of one of the following formulae:
6 . The compound of claim 1 , wherein the compound is a fluorinated trazodone of the following formula:
7 . The compound of claim 1 , wherein the compound is a fluorinated mirtazapine of the following formula:
8 . The compound of claim 1 , wherein the compound is a fluorinated amitriptyline of the following formula:
9 . The compound of claim 1 , wherein the compound is a fluorinated amoxapine of one of the following formulae:
10 . The compound of claim 1 , wherein the compound is a fluorinated clomipramine of the following formula:
11 . The compound of claim 1 , wherein the compound is a fluorinated imipramine of the following formula:
12 . The compound of claim 1 , wherein the compound is a fluorinated nortriptyline of the following formula:
13 . The compound of claim 1 , wherein the compound is a fluorinated trimipramine of the following formula:
14 . The compound of claim 1 , wherein the compound is a fluorinated maprotiline of the following formula:
15 . The compound of claim 1 , wherein the compound is a fluorinated nefazodone of one of the following formulae:
16 . The compound of claim 1 , wherein the compound is a fluorinated sibutramine.
17 . (canceled)
18 . The compound of claim 1 , wherein the compound is a fluorinated fluoxetine of the following formula:
19 .- 21 . (canceled)
22 . The compound of claim 1 , wherein the compound is a fluorinated doxepin of one of the following formulae:
23 . (canceled)
24 . The compound of claim 1 , wherein the compound is a fluorinated lofepramine of one of the following formulae:
25 .- 141 . (canceled)
142 . The compound of claim 1 , wherein the compound is a fluorinated venlafaxine of the following formula: