Absorbent foam wound dressing materials
A wound dressing material comprising a solid substrate having interstitial spaces therein, wherein said substrate is a hydrophilic open-cell foam material, and wherein said interstitial spaces are at least partially filled by a hydrophilic polyurethane foam different from said substrate foam material. Also provided is a method of making a porous wound dressing material comprising the steps of: providing a substrate of a solid hydrophilic first foam material; applying a fluid or gel polyurethane foam prepolymer mixture to at least one surface of said solid substrate; and curing said prepolymer in contact with said solid substrate.
1. A wound dressing material, comprising:
a solid substrate having a plurality of interconnected interstitial spaces therein, wherein said solid substrate is a hydrophilic open-cell foam material; and
a hydrophilic polyurethane foam forms a substantially continuous interstitial foam structure extending between the plurality of interconnected interstitial spaces of said solid substrate.
2. The wound dressing material of claim 1 , wherein said hydrophilic polyurethane foam is applied to one side only of said solid substrate.
3. The wound dressing material of claim 2 , wherein one surface of said wound dressing material consists essentially of said hydrophilic polyurethane foam.
4. A wound dressing comprising the wound dressing material of claim 1 .
5. The wound dressing of claim 4 which is sterile and packaged in a microorganism-impermeable container.
6. The wound dressing material of claim 1 , wherein said solid substrate is elastically compressible and exhibits an elongation at break of at least about 100%.
7. The wound dressing material of claim 1 , comprising from about 10 wt % to about 90 wt % of said hydrophilic polyurethane foam, based on total weight of the wound dressing material.
8. The wound dressing material of claim 1 , wherein said hydrophilic polyurethane foam has a basis weight of from about 0.2 to about 1.5 kg/rn2.
9. The wound dressing material of claim 1 , wherein the interstitial spaces are present in the solid substrate at from about 5 to about 30 pores per cm.
10. A method of making a porous wound dressing material comprising the steps of:
providing a substrate of a solid hydrophilic first foam material having a plurality of interconnected interstitial spaces therein;
applying a fluid or gel polyurethane foam prepolymer mixture to at least one surface of said substrate such that the fluid or gel polyurethane foam prepolymer mixture is distributed within the plurality of interconnected interstitial spaces of said substrate; and
curing said fluid or gel polyurethane foam prepolymer mixture to provide a hydrophilic polyurethane foam that forms a substantially continuous interstitial foam structure extending between the plurality of interconnected interstitial spaces of said substrate.
11. The method of claim 10 , wherein the fluid or gel polyurethane foam prepolymer mixture comprises: 1 part by weight of an isocyanate-capped prepolymer having from about 0.5 to about 1.2 meq NCO groups/g; from about 0.4 to about 1.0 parts by weight of water; and from about 0.05 to about 0.4 parts by weight of a C1 to C3 monohydric alcohol.
12. The method of claim 10 , wherein said step of applying comprises compressing and releasing said substrate in contact with said fluid or gel polyurethane foam prepolymer mixture to increase uptake of the fluid or gel polyurethane foam prepolymer mixture into the substrate.
13. The method of claim 10 , wherein said step of applying comprises: applying a solvent to said substrate, applying a layer of said fluid or gel polyurethane foam prepolymer mixture to said substrate, and allowing the fluid or gel polyurethane foam prepolymer mixture to impregnate the substrate.
14. The method of claim 10 further comprising sterilizing said wound dressing material.
15. The wound dressing material of claim 10 , wherein the interstitial spaces are present in the substrate at from about 5 to about 30 pores per cm.
16. A wound dressing material formed by a method comprising:
providing a substrate of a solid hydrophilic first foam material having a plurality of interconnected interstitial spaces therein;
applying a fluid or gel polyurethane foam prepolymer mixture to at least one surface of said substrate such that the fluid or gel polyurethane foam prepolymer mixture is distributed within the plurality of interconnected interstitial spaces of said substrate; and
curing said fluid or gel polyurethane foam prepolymer mixture to provide a hydrophilic polyurethane foam that forms a substantially continuous interstitial foam structure extending between the plurality of interconnected interstitial spaces of said substrate.
17. The wound dressing material of claim 16 , wherein the fluid or gel polyurethane foam prepolymer mixture comprises: 1 part by weight of an isocyanate-capped prepolymer having from about 0.5 to about 1.2 meq NCO groups/g; from about 0.4 to about 1.0 parts by weight of water; and from about 0.05 to about 0.4 parts by weight of a C1 to C3 monohydric alcohol.
18. The wound dressing material of claim 16 , wherein said step of applying comprises compressing and releasing said substrate in contact with said fluid or gel polyurethane foam prepolymer mixture to increase uptake of the fluid or gel polyurethane foam prepolymer mixture into the substrate.
19. The wound dressing material of claim 16 , wherein said step of applying comprises: applying a solvent to said substrate, applying a layer of said fluid or gel polyurethane foam prepolymer mixture to said substrate, and allowing the fluid or gel polyurethane foam prepolymer mixture to impregnate the substrate.
20. The wound dressing material of claim 10 , wherein the interstitial spaces are present in the substrate at from about 5 to about 30 pores per cm.