IP Library › Granted Patent US 8,507,651
Granted Patent B2
US 8,507,651 · App. 13/152,072 · Granted Aug 13, 2013

Treatment of diseases and conditions mediated by increased phosphorylation

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Quick Facts
Patent No.
US 8,507,651
App. No.
13/152,072
Granted
Aug 13, 2013
Kind
B2
Abstract

The invention provides methods for the treatment of diseases and conditions mediated by increased phosphorylation, such as inflammation and cancer. The invention also provides methods for the inhibition of increased phosphorylation in cells, tissues and organs. The methods utilize a phosphate acceptor compound (PAC). The invention also provides products comprising a PAC.

Claims (4)

1. A method to reduce the severity of eczema or a dermatitis mediated by increased phosphorylation in an animal comprising administering an effective amount of a partially dephosphorylated phosphate-acceptor compound (PAC) to said animal in need thereof, wherein the PAC is a phosvitin which is at least 10% to 70% dephosphorylated.

2. The method of claim 1 wherein the phosvitin is chicken phosvitin.

3. The method of claim 2 wherein the phosvitin fragment thereof is at least about 90% dephosphorylated.

4. The method of claim 1 wherein the phosvitin fragment thereof is at least about 90% dephosphorylated.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 9, 2013
From: DMI ACQUISITION CORP.
To: AMPIO PHARMACEUTICALS, INC.
Reel/Frame 031305/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 4, 2013
From: DMI BIOSCIENCES, INC.
To: DMI ACQUISITION CORP.
Reel/Frame 029565/0273 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 15, 2012
From: BAR-OR, DAVID
To: DMI BIOSCIENCES, INC.
Reel/Frame 029307/0214 →