IP Library Granted Patent US 9,095,276
Granted Patent B2
US 9,095,276 · App. 13/153,169 · Granted Aug 4, 2015

Breath end-tidal gas monitor

Inventors: Lee R. Carlson (Pleasanton, CA); Edward A. McClatchie (Orinda, CA); Joe Martinosky (Wildwood, MO); Ralph Walden (Granite City, IL); Elvir Causevic (Denver, CO)
Assignee: Capnia, Inc.
A61B5/083A61B5/08A61B5/087A61B5/0833A61B5/0836
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Quick Facts
Patent No.
US 9,095,276
App. No.
13/153,169
Granted
Aug 4, 2015
Kind
B2
Abstract

An improved apparatus and method for capturing and analyzing the end-tidal portion of an exhalation. The CO 2 level of air drawn into the system ( 10 ) is monitored to distinguish inhalation and exhalation of breath. Upon detection of a decrease in the CO 2 level in the air drawn into the system ( 10 ), indicating a transition between exhalation and inhalation a pair of flow selector valves ( 26, 28 ) are operated to capture the end-tidal volume of air drawn into the system ( 10 ) immediately prior to the detection of the decrease in the CO 2 level. Incoming air is diverted around the captured volume of air, and the CO 2 levels are continually monitored to ensure that the captured volume of air corresponds to the end-tidal portion of an exhalation. Once the captured volume of air is positively identified as the end-tidal portion of an exhalation, the captured volume is routed through a gas analyzer ( 44 ) for analysis of one or more predetermined gas levels.

Claims (8)

1. A breath gas analyzer having a pump configured to draw a flow of air through a capnograph adapted to identify a transition point between an exhalation and an inhalation, and to subsequently direct said flow of air through at least one gas analyzer, comprising: a first flow selector valve disposed downstream from said capnograph, said first flow selector valve configured to selectively divert said flow of air into a sample volume or into a bypass pathway for routing around said sample volume; a second flow selector valve disposed downstream from said first flow selector valve, said second flow selector valve configured to isolate said sample volume from said first flow selector valve; a third flow selector valve disposed downstream from said second flow selector valve, said third flow selector valve configured to receive said flow of air from said bypass pathway and to isolate said sample volume from said pump; a fourth flow selector valve disposed downstream from said pump, said fourth flow selector valve configured to selectively exhaust said flow of air or to route said flow of air into said sample volume; and wherein said second flow selector valve is further configured to selectively exhaust said sample volume through the at least one gas analyzer.

2. The breath gas analyzer of claim 1 wherein said second flow selector valve and said third flow selector valve are responsive to signals from said capnograph to isolate said sample volume from said first flow selector valve and from said pump.

3. The breath gas analyzer of claim 1 wherein said fourth flow selector valve is responsive to signals from said capnograph to route said flow of air into said sample volume.

4. The breath gas analyzer of claim 3 wherein said fourth flow selector valve is responsive to signals from said capnograph to route said flow of air through a one-way valve into said sample volume.

5. The breath gas analyzer of claim 1 wherein said second flow selector valve is responsive to signals from said capnograph to exhaust said sample volume through the at least one gas analyzer.

6. The breath gas analyzer of claim 1 wherein the at least one gas analyzer includes a CO gas analyzer.

7. The breath gas analyzer of claim 1 wherein the at least one gas analyzer includes an O 2 gas analyzer.

8. The breath gas analyzer of claim 1 further including a microprocessor configured to receive signals from said capnograph and to control operation of each of said flow selector valves.

Assignments (7)
CHANGE OF NAME Recorded Nov 17, 2017
From: CAPNIA, INC.
To: SOLENO THERAPEUTICS, INC.
Reel/Frame 044784/0981 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2011
From: CARLSON, LEE R.; MCCLATCHIE, EDWARD A.
To: EVEREST BIOMEDICAL INSTRUMENTS CO.
Reel/Frame 026738/0462 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2011
From: MARTINOSKY, JOE; WALDEN, RALPH
To: EVEREST BIOMEDICAL INSTRUMENTS CO.
Reel/Frame 026738/0474 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2011
From: CAUSEVIC, ELVIR
To: EVEREST BIOMEDICAL INSTRUMENTS CO.
Reel/Frame 026738/0483 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2011
From: EVEREST BIOMEDICAL INSTRUMENTS, CO.
To: STRYKER CORPORATION
Reel/Frame 026738/0499 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2011
From: STRYKER CORPORATION; EVEREST BIOMEDICAL INSTRUMENTS COMPANY
To: BIOMEDICAL DRUG DEVELOPMENT INC.
Reel/Frame 026738/0501 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2011
From: BIOMEDICAL DRUG DEVELOPMENT INC.
To: CAPNIA, INC.
Reel/Frame 026738/0508 →
Continuity (2)
Division 10561561
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