IP Library Granted Patent US 8,718,735
Granted Patent B2
US 8,718,735 · App. 13/153,349 · Granted May 6, 2014

Physiological parameter confidence measure

Inventors: Marcelo Lamego (Coto de Caza, CA); Mohamed Diab (Ladera Ranch, CA); Ammar Al-Ali (San Juan Capistrano, CA)
Assignee: Cercacor Laboratories, Inc.
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Quick Facts
Patent No.
US 8,718,735
App. No.
13/153,349
Granted
May 6, 2014
Kind
B2
Abstract

Confidence in a physiological parameter is measured from physiological data responsive to the intensity of multiple wavelengths of optical radiation after tissue attenuation. The physiological parameter is estimated based upon the physiological data. Reference data clusters are stored according to known values of the physiological parameter. At least one of the data clusters is selected according to the estimated physiological parameter. The confidence measure is determined from a comparison of the selected data clusters and the physiological data.

Claims (34)

1. A method of determining a measure of confidence in a physiological parameter, the physiological parameter determined by transmitting multiple wavelengths of optical radiation into a tissue site and detecting the optical radiation after tissue attenuation, the method comprising:

deriving physiological data responsive to the intensity of three or more wavelengths of optical radiation transmitted into a tissue site and detected after tissue attenuation;

estimating a physiological parameter based upon the physiological data;

providing a plurality of data sets, each of the data sets based on related predetermined physiological data at the three or more wavelengths;

selecting at least one data set from the plurality of data sets based on the estimated physiological parameter; and

determining a measure of confidence in the estimated physiological parameter based upon the selected at least one data set and the derived physiological data.

2. The method according to claim 1 , wherein the providing step comprises:

predetermining the physiological data for known values of the physiological parameter across a sample population;

grouping the data into sets according to the physiological parameter values; and

storing the data sets so as to be retrievable according to the physiological parameter values.

3. The method according to claim 1 , wherein the selecting step comprises:

determining at least one data set having a corresponding physiological parameter value closest to the estimated physiological parameter; and

reading the determined at least one data set from the memory.

4. The method according to claim 3 , wherein the physiological data comprise ratios of normalized plethysmographs.

5. The method according to claim 4 , wherein the physiological parameter comprises SpO2, MetHb or HbCO.

6. The method according to claim 5 , wherein the data sets comprise a plurality of parametric curves of normalized plethysmograph ratio versus wavelength.

7. The method according to claim 1 , further comprising:

activating a probe-off alarm when the measure of confidence is less than a predetermined value.

8. The method according to claim 1 , further comprising:

activating a probe-off alarm when the measure of confidence falls outside a predetermined region.

9. A confidence measurement system comprising:

a sensor configured to provide data responsive to the intensity of three or more wavelengths of optical radiation transmitted into a tissue site and detected after tissue attenuation;

a preprocessor configured to receive data from the sensor and determine a plurality of physiological data therefrom;

a parameter estimator configured to receive the plurality of physiological data and output an estimate of a physiological parameter;

a data element configured to store a plurality of data sets corresponding to known values of the physiological parameter and based on related predetermined physiological data at the three or more wavelengths; and

a confidence measurer adapted to compare the plurality of physiological data with the plurality of data sets so as to select at least one data set based on at least the physiological parameter estimate and calculate a measure of confidence in the physiological parameter estimate based on the selected at least one data set and the plurality of physiological data.

10. The confidence measurement system according to claim 9 , wherein the plurality of physiological data comprises a plurality of ratios of normalized plethysmographs corresponding to the three or more wavelengths of optical radiation.

11. The confidence measurement system according to claim 10 , wherein the parameter estimator is further configured to output an estimate of at least one of SpO2, HbCO, HbMet, Hbt, fractional oxygen saturation, bilirubin or glucose.

12. The confidence measurement system according to claim 11 , wherein the plurality of data sets comprise a plurality of known values of the physiological parameter, corresponding predetermined values of ratios of normalized plethysmographs, and probabilities associated with the predetermined values.

13. The confidence measurement system according to claim 9 further comprising:

a probe-off alarm activated when the measure of confidence is less than a predetermined value.

14. The confidence measurement system according to claim 9 further comprising:

a probe-off alarm activated when the measure of confidence falls outside a predetermined region.

15. The confidence measurement system according to claim 9 , wherein the plurality of data sets comprise a plurality of parametric curves of normalized plethysmograph ratio versus wavelength.

Assignments (3)
CHANGE OF NAME Recorded May 16, 2024
From: CERCACOR LABORATORIES, INC.
To: WILLOW LABORATORIES, INC.
Reel/Frame 067455/0298 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 19, 2016
From: LAMEGO, MARCELO; DIAB, MOHAMED K.; AL-ALI, AMMAR
To: MASIMO LABORATORIES, INC.
Reel/Frame 040063/0402 →
CHANGE OF NAME Recorded May 21, 2012
From: MASIMO LABORATORIES, INC.
To: CERCACOR LABORATORIES, INC.
Reel/Frame 028246/0087 →
Continuity (6)
Continuation 11367034 · Mar 1, 2006
Provisional Application 60657596 · Mar 1, 2005
Provisional Application 60657281 · Mar 1, 2005
Provisional Application 60657268 · Mar 1, 2005
Provisional Application 60657759 · Mar 1, 2005
Related Publication 20110237914A1 · Sep 29, 2011