Device for delivering medicinal implants

1. A device for inserting a medicament within a body cavity of a mammal, said device comprising:

a cartridge for containing said medicament therein, said cartridge comprising:

a housing comprising a proximal portion and a distal portion,

a retractable chamber disposed within said housing, said retractable chamber comprising an internal surface, an external surface and a lumen defined by said internal surface,

a substantially stationary member disposed within said lumen of said retractable chamber, said substantially stationary member having a uniform cross-section sized to provide a sliding fit within said lumen to provide for retraction of said retractable chamber about said substantially stationary member upon actuation of said device, and

means for retracting said retractable chamber about said substantially stationary member while maintaining said substantially stationary member in a substantially stationary position upon actuation of said device; and

means for activating said means for retracting said retractable chamber.

2. The device of claim 1 , further comprising:

an actuator for placing said device in operation, said actuator comprising:

the means for activating said means for retracting said retractable chamber, and

a handle case comprising a distal portion comprising means for attaching said actuator to said cartridge,

wherein said proximal portion of said housing comprises means for connecting said cartridge to said actuator, and wherein said proximal portion of said housing is connected to said distal portion of said handle case, whereby said cartridge and said actuator are connected in operational engagement.

3. The device of claim 1 , further comprising multiple doses of said medicament.

4. The device of claim 1 , wherein said medicament comprises a dry microparticle composition.

5. The device of claim 1 , wherein said medicament is selected from the group consisting of antibacterials, antibiotics, antifungal agents, anti-inflammatory agents, immunosuppressive agents, immunostimulatory agents, dentinal desensitizers, odor masking agents, immune reagents, anesthetics, antiseptics, nutritional agents, antioxidants, lipopolysaccharide complexing agents, peroxides and growth factors.

6. The device of claim 1 , wherein said cavity is a periodontal pocket of said mammal.

7. The device of claim 1 , wherein said means for attaching said actuator to said cartridge located at said distal portion of said handle case comprises a tube tip comprising an undercut on its inner surface.

8. The device of claim 1 , wherein a distal tip of said retractable chamber has a uniform external cross-section sized to fit within said body cavity.

9. A cartridge for use in a device for inserting a medicament within a cavity of a mammal, said cartridge comprising:

a housing comprising a proximal portion and a distal portion;

a retractable chamber disposed within said housing, said retractable chamber comprising a distal end, an internal surface, an external surface and a lumen having a uniform cross-section sized to contain said medicament therein, said lumen defined by said internal surface, said retractable chamber sized to fit within and extend from said distal portion of said housing;

a substantially stationary member disposed within said lumen of said retractable chamber, said substantially stationary member having a uniform cross-section sized to provide a sliding fit within said lumen suitable to provide for retraction of said retractable chamber about said substantially stationary member upon actuation of said device; and

means for retracting said retractable chamber about said substantially stationary member while maintaining said substantially stationary member in a substantially stationary position upon actuation of said device.

10. The cartridge of claim 9 , wherein said proximal portion of said housing comprises means for connecting said cartridge to a distal portion of said actuator of said device,

whereby upon connection of said proximal portion of said housing to said distal portion of said actuator, said cartridge and said actuator are placed in operational engagement.

11. The cartridge of claim 9 , wherein the cartridge is configured to contain the medicament therein for use in the device, the device comprising the cartridge and an actuator for placing the device in operation.

12. The cartridge of claim 9 , wherein said means for connecting said cartridge to said distal portion of said actuator comprises flanges for engaging an undercut on a tube tip positioned at said distal portion of said actuator.

13. The cartridge of claim 9 , wherein said means for retracting said retractable chamber comprises a spring disposed about said retractable chamber for retracting said retractable chamber about said substantially stationary member.

14. The cartridge of claim 9 , wherein said medicament is selected from the group consisting of tetracycline, a pharmaceutically acceptable salt of a tetracycline, hydrates of a tetracycline and hydrates of a pharmaceutically acceptable salt of a tetracycline.

15. An actuator for use in a device for dispensing medicaments to a cavity of a mammal, said actuator comprising:

a handle case having a proximal portion for gripping and a distal portion comprising means for attaching said actuator to a cartridge for containing medicament; and

means for creating a proximal to distal linear motion with respect to said handle case,

wherein said cartridge comprises a retractable chamber for containing said medicament disposed therein, a substantially stationary member and means for retracting said retractable chamber about said substantially stationary member while maintaining said substantially stationary member in a substantially stationary position, and

whereby upon attachment of said actuator to said cartridge and actuation of said device by said actuator, said means for creating a proximal to distal linear motion interacts with said means for retracting said retractable chamber and is effective to provide for retraction of said retractable chamber about said substantially stationary member.

16. The actuator of claim 15 , wherein a proximal end of said retractable chamber of said cartridge is engaged with a distal end of a cannulated inner sleeve disposed in said handle case.

17. The actuator of claim 15 , wherein said means for attaching said actuator to a cartridge comprises a tube tip with an undercut.

18. The actuator of claim 15 , wherein said means for creating said proximal to distal linear motion with respect to said handle case comprises means of converting rotational motion to linear motion.

19. The actuator of claim 18 , wherein said means for converting rotational motion to linear motion comprises an operating lever located on an upper surface of said distal portion of said handle case; wherein said operating lever comprises a finger-manipulating portion, a pin and a lobe, wherein said lobe is engaged with a vertical wall with flat surface disposed on said cannulated inner sleeve, and whereby displacement of said operating lever towards said handle case displaces said cannulated inner sleeve in said proximal to distal motion with respect to said handle case.

20. The actuator of claim 18 , wherein said means for converting rotational motion to linear motion comprises a trigger located on an lower surface of said distal portion of said handle case; wherein said trigger comprises a finger-manipulating portion, a rotation pin and a slot, wherein a pin attached to said cannulated inner sleeve is engaged with said slot, and whereby displacement of said trigger towards said handle case displaces said cannulated inner sleeve in said proximal to distal motion with respect to said handle case.