NASAL DEVICES
Described herein are adhesive nasal devices. In particular, the adhesive nasal respiratory devices described herein are configured to be worn in communication with a subject's nasal cavity and may include a rim body having a passageway therethrough, an airflow resistor in communication with the passageway of the rim body, and a flexible, adhesive holdfast layer extending outward from the periphery of the rim body. The rim body region may be formed from multiple parts (e.g., a first and a second rim body region), and the airflow resistor may be secured between the parts forming the rim body. Methods of manufacturing and assembling these adhesive nasal devices are also described.
1 . A nasal device adapted to be secured in communication with a subject's nasal cavity, the device comprising:
an airflow resistor configured to inhibit airflow during expiration more than airflow during inspiration; and
a flexible, adhesive holdfast and
wherein the airflow resistor is configured to have a resistance to expiration between about 5 cm H 2 O/(L/sec) and about 250 cm H 2 O/(L/sec) when resistance is measured at a flow rate of 100 ml/sec.
2 . The device of claim 1 , wherein the flexible, adhesive holdfast extends outward from the airflow resistor.
3 . The device of claim 1 , wherein the flexible, adhesive holdfast is configured to seal the nasal device around the subject's nostril.
4 . The device of claim 1 , further comprising an internally-projecting region at least partially surrounding the airflow resistor configured to project into the subject's nostril.
5 . The device of claim 1 , wherein the flexible, adhesive holdfast is adapted to be secured in communication with both of a subject's nostrils.
6 . The device of claim 1 , further comprising a leak pathway through the nasal device configured to be open during both expiration and inspiration.
7 . The device of claim 1 , wherein the airflow resistor comprises a flap valve.
8 . A nasal device adapted to be secured in communication with a subject's nasal cavity, the device comprising:
an airflow resistor, wherein the airflow resistor is configured to inhibit airflow during expiration more than airflow during inspiration; and
a flexible, adhesive holdfast configured to seal the nasal device around the subject's nostril.
9 . The device of claim 8 , wherein the flexible, adhesive holdfast extends outward from the airflow resistor.
10 . The device of claim 8 , further comprising an internally-projecting region at least partially surrounding the airflow resistor configured to project into the subject's nostril.
11 . The device of claim 8 , wherein the flexible, adhesive holdfast is adapted to be secured in communication with both of a subject's nostrils.
12 . The device of claim 8 , further comprising a leak pathway through the nasal device configured to be open during both expiration and inspiration.
13 . The device of claim 8 , wherein the airflow resistor comprises a flap valve.
14 . A nasal device adapted to be secured in communication with a subject's nasal cavity, the device comprising:
an airflow resistor configured to inhibit airflow during expiration more than airflow during inspiration; and
a flexible, adhesive holdfast and
further comprising a protective cover configured to be removed from the adhesive holdfast to expose at least a portion of the biocompatible adhesive.
15 . The device of claim 14 , wherein the flexible, adhesive holdfast extends outward from the airflow resistor.
16 . The device of claim 14 , wherein the flexible, adhesive holdfast is configured to seal the nasal device around the subject's nostril.
17 . The device of claim 14 , further comprising an internally-projecting region at least partially surrounding the airflow resistor configured to project into the subject's nostril.
18 . The device of claim 14 , wherein the flexible, adhesive holdfast is adapted to be secured in communication with both of a subject's nostrils.
19 . The device of claim 14 , further comprising a leak pathway through the nasal device configured to be open during both expiration and inspiration.
20 . The device of claim 14 , wherein the airflow resistor comprises a flap valve.