IP Library Granted Patent US 9,364,168
Granted Patent B2
US 9,364,168 · App. 13/174,665 · Granted Jun 14, 2016

Methods and systems for endobronchial diagnosis

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Quick Facts
Patent No.
US 9,364,168
App. No.
13/174,665
Granted
Jun 14, 2016
Kind
B2
Abstract

A method of diagnosing an air leak in a lung compartment of a patient may include: advancing a diagnostic catheter into an airway leading to the lung compartment; inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment; measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter; displaying the measured air pressure as an air pressure value on a console coupled with the diagnostic catheter; and determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths.

Claims (16)

1. A method of diagnosing an air leak in a lung compartment of a patient, the method comprising:

advancing a diagnostic catheter into an airway leading to the lung compartment;

inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment;

measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter;

measuring air flow out of the lung compartment during the multiple breaths, using the catheter;

displaying the measured air pressure as an air pressure value and displaying the measured air flow as an air flow value on a console coupled with the diagnostic catheter; and

determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths by correlating a negative base-line value to the presence of the air leak and by determining a ratio of inspiratory to expiratory flow; and

correlating said negative base-line value and the ratio with a size of the air leak.

2. The method of claim 1 , wherein the console displays multiple air pressure values measured during the multiple breaths as a wave-form.

3. The method of claim 1 , further comprising displaying on the console whether the air leak is present in the compartment.

4. The method of claim 1 , wherein the lung compartment comprises a lobe of a lung.

5. The method of claim 1 , wherein the lung compartment comprises a segment of a lung.

6. The method of claim 1 , further comprising:

using the diagnostic catheter to assess whether there is collateral ventilation into the lung compartment; and

determining a treatment method based on the determinations of the air leak and collateral ventilation.

7. The method of claim 1 , further comprising repeating the steps to assess at least one additional lung compartment.

Assignments (9)
RELEASE OF SECURITY INTEREST Recorded Mar 4, 2026
From: CANADIAN IMPERIAL BANK OF COMMERCE
To: PULMONX CORPORATION
Reel/Frame 075028/0274 →
SECURITY INTEREST Recorded Mar 2, 2026
From: PULMONX CORPORATION
To: PERCEPTIVE CREDIT HOLDINGS V, LP, AS ADMINISTRATIVE AGENT
Reel/Frame 075012/0453 →
SECURITY INTEREST Recorded Jan 27, 2026
From: PULMONX CORPORATION
To: CANADIAN IMPERIAL BANK OF COMMERCE
Reel/Frame 074570/0001 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2020
From: OXFORD FINANCE LLC, AS COLLATERAL AGENT
To: PULMONX CORPORATION
Reel/Frame 053952/0044 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2020
From: BOSTON SCIENTIFIC CORPORATION
To: PULMONX CORPORATION
Reel/Frame 053953/0548 →
SECURITY INTEREST Recorded Mar 2, 2020
From: PULMONX CORPORATION
To: CANADIAN IMPERIAL BANK OF COMMERCE
Reel/Frame 052916/0213 →
SECURITY INTEREST Recorded Jul 26, 2017
From: PULMONX CORPORATION
To: BOSTON SCIENTIFIC CORPORATION
Reel/Frame 043349/0725 →
SECURITY INTEREST Recorded May 15, 2017
From: PULMONX CORPORATION
To: OXFORD FINANCE LLC, AS COLLATERAL AGENT
Reel/Frame 042466/0349 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2011
From: MANTRI, SURAG
To: PULMONX CORPORATION
Reel/Frame 027251/0627 →