Ultrasound therapy system
View Patent ↗In one embodiment of the present invention, a system for treating an occlusion within a patient's vasculature with ultrasonic energy comprises a catheter configured to be passed through the patient's vasculature such that a portion of the catheter is positioned at an intravascular treatment site. The system further comprises an ultrasound radiating member, an ultrasound signal generator configured to supply a drive signal to the ultrasound radiating member, an infusion pump configured to pump a therapeutic compound into the fluid delivery lumen so as to cause the therapeutic compound to be delivered to the treatment site and a controller configured to control the ultrasound signal generator and the infusion pump.
1. An apparatus comprising:
a catheter body that is elongate and hollow, the catheter body having a distal region, a proximal region opposite the distal region, and an exterior surface;
an ultrasound radiating member positioned with the distal region of the catheter body;
a fluid delivery lumen extending between the proximal region and the distal region of the catheter body; and
a plurality of holes forming surface features on the exterior surface of the distal region of the catheter body, the plurality of holes having a diameter between approximately 1 and 100 μm, wherein the plurality of holes are not formed in the ultrasound radiating member and do not extend through the catheter body.
2. The apparatus of claim 1 , further comprising a fluid delivery port formed in the distal region of the catheter body, the fluid delivery port being hydraulically connected to the fluid delivery lumen.
3. The apparatus of claim 1 , wherein the plurality of holes are formed using an ablative laser.
4. The apparatus of claim 1 , wherein the plurality of holes are separated from each other by an average distance that is between approximately 1 μm and approximately 100 μm.
5. The apparatus of claim 1 , wherein the plurality of holes are positioned adjacent to the ultrasound radiating member.
6. The apparatus of claim 1 , further comprising a plurality of ultrasound radiating members positioned within the distal region of the catheter body.