IP Library Granted Patent US 9,125,570
Granted Patent B2
US 9,125,570 · App. 13/184,482 · Granted Sep 8, 2015

Real-time tomosynthesis guidance for radiation therapy

Inventors: Norbert Joseph Pelc (Los Altos, CA); Rebecca Fahrig (Palo Alto, CA); Joseph Anthony Heanue (Oakland, CA); Edward Gerald Solomon (Menlo Park, CA); Brian Patrick Wilfley (Los Altos, CA)
Assignees: The Board of Trustees of the Leland Stanford Junior University; Triple Ring Technologies, Inc.
A61B6/025A61B6/12A61B6/4014A61B6/4028A61N5/1049A61N5/1067A61N5/1071G06T7/0012G06T11/003A61B6/032A61B6/4007A61B6/4241A61N5/1065A61N5/1069A61N2005/1061
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Quick Facts
Patent No.
US 9,125,570
App. No.
13/184,482
Granted
Sep 8, 2015
Kind
B2
Abstract

The present invention pertains to an apparatus and method for delivering radiation to a human patient or other mammal. A scanning electron beam x-ray source is used and the detector can be a photon counting detector. The area of the detector is less than the area of field of view in the patient. Tomosynthesis can be used to generate images and images can be produced rapidly in real time.

Claims (27)

1. A method for delivering radiation therapy to a mammal comprising:

scanning an electron beam over an x-ray target to produce x-rays from a plurality of x-ray focal spots;

directing said x-rays towards an imaging field of view and a specified object in said imaging field of view in said mammal;

measuring amount of said x-rays striking a detector with an active imaging area smaller than an area of said imaging field of view;

producing a first pixel representation of said object based on amount of said x-rays striking said detector from a first x-ray focal spot of said plurality of x-ray focal spots;

producing a second pixel representation of said object based on amount of said x-rays striking said detector from a second x-ray focal spot of said plurality of x-ray focal spots;

tracking movement of said object using said first pixel representation and said second pixel representation;

analyzing image quality of said object in each plane of a plurality of planes;

identifying a single plane of best focus of said object from said plurality of planes based on said analyzed image quality;

identifying position of said object along a direction corresponding to plane displacement based on said single plane of best focus; and

controlling radiation from a radiation therapy source towards said object.

2. The method for delivering radiation therapy of claim 1 further comprising:

enabling said radiation therapy source when said object is aligned with said radiation therapy source.

3. The method for delivering radiation therapy of claim 1 further comprising:

disabling said radiation therapy source when said object is not aligned with said radiation therapy source.

4. The method for delivering radiation therapy of claim 1 further comprising:

adjusting position of said radiation therapy source to align said radiation therapy source with said object.

5. The method for delivering radiation therapy of claim 1 further comprising:

adjusting position of said mammal to align said radiation therapy source with said object.

6. The method for delivering radiation therapy of claim 1 further comprising:

refreshing said first pixel representation and said second pixel representation at least every 2 seconds.

7. The method for delivering radiation therapy of claim 1 further comprising:

generating a tomosynthesis image of said object using said first pixel representation and said second pixel representation.

8. The method for delivering radiation therapy of claim 1 further comprising:

tracking actual radiation dose delivered to said object.

9. The method for delivering radiation therapy of claim 1 further comprising:

creating a treatment plan to deliver a specified radiation dose to said object.

Assignments (10)
RELEASE OF SECURITY INTEREST Recorded Dec 6, 2024
From: SILICON VALLEY BANK, A DIVISION OF FIRST-CITIZENS BANK & TRUST COMPANY
To: TRIPLE RING TECHNOLOGIES, INC.
Reel/Frame 069514/0534 →
RELEASE OF SECURITY INTEREST Recorded Dec 16, 2023
From: AGILITY CAPITAL III, LLC
To: TRIPLE RING TECHNOLOGIES, INC.
Reel/Frame 066047/0749 →
SECURITY INTEREST Recorded May 2, 2022
From: TRIPLE RING TECHNOLOGIES, INC.
To: SILICON VALLEY BANK
Reel/Frame 059783/0582 →
SECURITY INTEREST Recorded Apr 22, 2022
From: TRIPLE RING TECHNOLOGIES, INC.
To: AGILITY CAPITAL III, LLC
Reel/Frame 059687/0030 →
RELEASE OF SECURITY INTEREST Recorded Apr 14, 2022
From: WESTERN ALLIANCE BANK, AS SUCCESSOR IN INTEREST TO BRIDGE BANK, NATIONAL ASSOCIATION
To: TRIPLE RING TECHNOLOGIES, INC.
Reel/Frame 059605/0827 →
RELEASE OF SECURITY INTEREST Recorded Aug 25, 2017
From: AGILITY CAPITAL II, LLC
To: TRIPLE RING TECHNOLOGIES, INC.
Reel/Frame 043414/0183 →
RELEASE OF SECURITY INTEREST Recorded Sep 23, 2014
From: AVIDBANK CORPORATE FINANCE, A DIVISION OF AVIDBANK
To: TRIPLE RING TECHNOLOGIES, INC.
Reel/Frame 033801/0730 →
SECURITY INTEREST Recorded Aug 12, 2014
From: TRIPLE RING TECHNOLOGIES, INC.
To: BRIDGE BANK, NATIONAL ASSOCIATION
Reel/Frame 033521/0778 →
SECURITY INTEREST Recorded Aug 12, 2014
From: TRIPLE RING TECHNOLOGIES, INC.
To: AGILITY CAPITAL II, LLC
Reel/Frame 033521/0804 →
SECURITY AGREEMENT Recorded Mar 3, 2014
From: TRIPLE RING TECHNOLOGIES, INC.
To: AVIDBANK
Reel/Frame 032379/0181 →
Continuity (2)
Provisional Application 61365289 · Jul 16, 2010
Related Publication 20120014501A1 · Jan 19, 2012