IP Library › Granted Patent US 8,241,574
Granted Patent B2
US 8,241,574 · App. 13/192,992 · Granted Aug 14, 2012

Ophthalmic device comprising a holographic sensor

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Quick Facts
Patent No.
US 8,241,574
App. No.
13/192,992
Granted
Aug 14, 2012
Kind
B2
Abstract

An ophthalmic device which comprises a holographic element comprising a medium comprising a phenylboronic acid group and, disposed therein, a hologram, wherein an optical characteristic of the element changes as a result of a variation of a physical property of the medium, and wherein the variation arises as a result of interaction between the medium and an analyte present in an ocular fluid.

Claims (16)

1. An ophthalmic device which comprises a holographic element comprising a medium comprising a phenylboronic acid group and, disposed therein, a reflection hologram,

wherein an optical characteristic of the element changes as a result of a variation of a physical property of the medium,

wherein the variation arises as a result of interaction between the medium and an analyte present in an ocular fluid, and

wherein an image of the reflection hologram is responsive to invisible radiation.

2. The device according to claim 1 , wherein the medium consists essentially of a polymer comprising the phenylboronic acid group.

3. The device according to claim 2 , wherein the medium consists of the polymer comprising the phenylboronic acid group.

4. The device according to claim 1 , wherein the phenylboronic acid group is selected from the group consisting of:

5. The device according to claim 1 , wherein the phenylboronic acid group is selected from the group consisting of:

6. The device according to claim 1 , wherein the holographic element does not contain silver.

7. The device according to claim 1 , wherein the interaction is a reversible chemical reaction.

8. The device according to claim 1 , wherein the analyte is glucose.

9. The device according to claim 1 , wherein the medium is a polymer of monomers including acrylamide.

10. The device according to claim 1 , wherein the medium is a polymer of monomers including 3-acrylamidophenylboronic acid.

11. The device according to claim 10 , wherein the medium comprises a group which is capable of repelling lactate, the group comprising a substantial negative charge.

12. The device according to claim 10 , wherein the medium comprises an amine group.

13. The device according to claim 1 , wherein the ophthalmic device is a contact lens.