Device and method for delivering mechanically released cells from liposuction aspirates
View Patent ↗A lipoaspirate collection device to aid in the collection and processing of human tissue and fluid obtained during liposuction for use in point-of-care cell therapy. The collection device includes a collection body and a collection cap. The collection cap may have a fluid port, a lipoaspirate port, a vacuum port, and a relief valve. Within the central cavity of the collection device, a cone shaped may be positioned such that the apex of the cone is positioned underneath the lipoaspirate inlet through which the lipoaspirate fluid and tissue are introduced.
1. A device to facilitate the collection and processing of mechanically released adipose derived progenitor and/or stem cells from fluid obtained during liposuction, comprising:
a collection body having an upper collection body cap wherein the collection body cap has a fluid port for introducing fluids, a lipoaspirate port through which lipoaspirate is introduced, a vacuum port, and a relief valve port, wherein the collection body has a central cavity in which is positioned a cone shaped deflector such that the apex of the cone is positioned pointed toward the upper collection body cap and such that the apex is positioned underneath the lipoaspirate inlet, and wherein the deflector is attached to the inner wall of the collection body via a plurality of struts that maintain the position and orientation of the deflector within the central cavity.
2. The device of claim 1 , wherein the cone includes a series of holes positioned near the apex of the cone to prevent an air lock, wherein the holes may optionally be covered by a disc to deflect tissue away from the holes.
3. The device of claim 1 wherein the collection body has a substantially cylindrical shape.
4. The device of claim 2 , further comprising:
a debris capturing trough or pit, constructed with various micro-texturing patterns to facilitate the retention of debris and circumferentially disposed along the inner wall of the collection body beneath the circular base of the cone shaped deflector; the trough optionally including a lip to help capture any sinking debris and the collection body further including a pit beneath the debris capturing trough to collect any additional sinking debris.
5. The device of claim 2 , further comprising:
at least one fluid recovery outlet to remove fluid from the collection body, and optionally an additional filter placed adjacent to the fluid recovery outlet to prevent any additional debris from leaving the collection body.
6. The device of claim 4 comprising:
needleless entry technology, so that it can be maintained in a sterile manner, but is readily accessible for connecting to a tube for removing the fluid.
7. The device of claim 4 wherein the fluid recovery outlet is laterally positioned above the pit of claim 3 , so that only fluid exits through the fluid recovery outlet.