IP Library › Granted Patent US 8,852,650
Granted Patent B2
US 8,852,650 · App. 13/211,855 · Granted Oct 7, 2014

Use of BBI/BBIC for treatment of muscular atrophy and degenerative muscle disease

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Quick Facts
Patent No.
US 8,852,650
App. No.
13/211,855
Granted
Oct 7, 2014
Kind
B2
Abstract

Methods for use of a composition comprising Bowman-Birk Inhibitor (BBI) or a derivative thereof in the treatment and/or prevention of skeletal muscle atrophy, to improve of skeletal muscle function, and to alleviate symptoms and/or slow progression of degenerative skeletal muscle diseases or disorders are provided.

Claims (4)

1. A method for increasing muscle mass, absolute force of a muscle, and/or cross-sectional area of muscle fibers, while maintaining specific muscle force in a mammal in need thereof comprising administering to the mammal a composition comprising a therapeutically effective amount of a capsule containing a Bowman-Birk Inhibitor.

2. The method of claim 1 wherein the composition is administered as a dietary supplement.

3. The method of claim 1 wherein the Bowman-Birk Inhibitor is in a concentrated form.

4. The method of claim 1 , wherein the mammal is an mdx mouse.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Jul 14, 2020
From: MIDCAP FINANCIAL TRUST, AS AGENT
To: PTC THERAPEUTICS, INC.
Reel/Frame 053209/0872 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCLUSION OF 6420591,6583309,6503713, 5843995,7029846,7056656, 6468969,6486305,6630294, 6989256,6627398,8247167, 9017935 PREVIOUSLY RECORDED ON REEL 042418 FRAME 0774. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST. Recorded Aug 24, 2017
From: PTC THERAPEUTICS, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 043672/0096 →
SECURITY INTEREST Recorded May 8, 2017
From: PTC THERAPEUTICS, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 042418/0774 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 19, 2011
From: SWEENEY, H. LEE; MORRIS, CARL A.; KENNEDY, ANN R.
To: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Reel/Frame 026776/0380 →