IP Library Granted Patent US 8,571,174
Granted Patent B2
US 8,571,174 · App. 13/229,147 · Granted Oct 29, 2013

Methods and systems for detecting possible error in patient position

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Quick Facts
Patent No.
US 8,571,174
App. No.
13/229,147
Granted
Oct 29, 2013
Kind
B2
Abstract

Systems and methods for automatically and dynamically modifying an image acquisition parameter for use in tomosynthesis breast imaging. A selected image acquisition parameter is modified in response to a measured characteristic of an imaged object such as a breast, and thus tailored to provide the highest quality image for the particular object. For example, image quality in a breast tomosynthesis system can be improved by dynamically varying motion and other acquisition parameters of the tomosynthesis system in response to physical characteristics of the breast to be imaged (determined during image acquisition), such as the breast thickness, density or composition. Dynamically varying acquisition or processing methods helps to customize the system for each particular patient, thereby improving image quality and identification and assessment of potential pathologies and abnormalities, and lower radiation dose, and thus a reduced the risk of long-term adverse health effects due to lifetime accumulated radiation dose.

Claims (33)

1. A method for detecting a possible patient positioning error during x-ray breast image acquisition, the method comprising:

positioning, under the control of a user of an image acquisition device, a breast of a patient into a first compressed imaging position according to a first view of the image acquisition device;

acquiring a first mammographic image of the breast in the first compressed imaging position;

positioning, under the control of the user, the breast into a second compressed imaging position according to a second view of the image acquisition device;

acquiring a second mammographic image of the breast in the second compressed imaging position;

processing the first and second mammographic images to compute, for each of the first and second mammographic images, at least one breast volume assessment metric;

comparing the at least one breast volume assessment metric for the first mammographic image to the at least one breast volume assessment metric for the second mammographic image and, if the breast volume assessment metrics differ by more than a threshold amount, activating at least one user interface device associated with the image acquisition device that alerts the user of a possible breast positioning error based at least in part upon the difference.

2. The method of claim 1 , wherein the breast volume assessment metric comprises at least one of a total breast volume (Vb), a fibroglandular tissue volume (Vfg), and a ratio (Vfg/Vb) of fibroglandular tissue volume to total breast volume.

3. The method of claim 1 , wherein the first view is a craniocaudal (CC) view and the second view is a mediolateral oblique (MLO) view.

4. The method of claim 1 , the first and second mammographic images being acquired by the image acquisition device comprising an x-ray imaging apparatus.

5. A computer-implemented for detecting a possible patient positioning error during x-ray breast image acquisition, the method comprising:

a computerized image acquisition device acquiring a first mammographic image of a breast in a first compressed imaging position according to a first view, wherein the breast was positioned by a user of the image acquisition device into the first compressed imaging position according to the first view;

the image acquisition device acquiring a second mammographic image of the breast in a second compressed imaging position according to a second view, wherein the breast was positioned by the user into the second compressed imaging position according to the second view;

the image acquisition device processing the first and second mammographic images to compute, for each of the first and second mammographic images, at least one breast volume assessment metric;

the image acquisition device comparing the at least one breast volume assessment metric for the first mammographic image to the at least one breast volume assessment metric for the second mammographic image and, if the breast volume assessment metrics differ by more than a threshold amount, activating at least one user interface device associated with the image acquisition device that alerts the user of a possible breast positioning error based at least in part upon the difference.

6. A method for detecting a possible patient positioning error during x-ray breast image acquisition, the method comprising:

positioning, under the control of user of an image acquisition device, a first breast of a patient into a first compressed imaging position according to a first view of the image acquisition device;

acquiring a first mammographic image of the first breast in the first compressed imaging position;

positioning, under the control of the user, a second breast of the patient into a second compressed imaging position according to a second view of the image acquisition device, the second breast being opposite the first breast;

acquiring a second mammographic image of the second breast in the second compressed imaging position;

processing the first and second mammographic images to compute, for each of the first and second mammographic images, at least one breast volume assessment metric;

comparing the at least one breast volume assessment metric for the first mammographic image to the at least one breast volume assessment metric for the second mammographic image and, if the breast volume assessment metrics differ by more than a threshold amount, activating at least one user interface device associated with the image acquisition device that alerts the user of a possible breast positioning error based at least in part upon the difference.

7. The method of claim 6 , wherein the breast volume assessment metric comprises at least one of a total breast volume (Vb), a fibroglandular tissue volume (Vfg), and a ratio (Vfg/Vb) of fibroglandular tissue volume to total breast volume.

8. The method of claim 6 , wherein the first view and the second view are the same view of the first and second breasts.

9. The method of claim 8 , wherein the first view and the second view are a craniocaudal (CC) view or a mediolateral oblique (MLO) view.

10. The method of claim 6 , wherein the first view and the second view are different views of the first and second breasts.

11. The method of claim 10 , wherein the first view is a craniocaudal (CC) view, and the second view is a mediolateral oblique (MLO) view.

12. The method of claim 6 , the first and second mammographic images being acquired by the image acquisition device comprising an x-ray imaging apparatus.

13. A computer-implemented method for detecting a possible patient positioning error during x-ray breast image acquisition, the method comprising:

a computerized image acquisition device acquiring a first mammographic image of a first breast in a first compressed imaging position, wherein the first breast was positioned by a user of the image acquisition device into the first compressed imaging position according to a first view;

the image acquisition device acquiring a second mammographic image of the second breast in a second compressed imaging position according to a second view, wherein the breast was positioned by the user into the second compressed imaging position according to the second view;

the image acquisition device processing the first and second mammographic images to compute, for each of the first and second mammographic images, at least one breast volume assessment metric;

the image acquisition device comparing the at least one breast volume assessment metric for the first mammographic image to the at least one breast volume assessment metric for the second mammographic image and, if the breast volume assessment metrics differ by more than a threshold amount, activating at least one user interface device associated with the image acquisition device that alerts the user of a possible breast positioning error based at least in part upon the difference.

Assignments (6)
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →