IP Library Granted Patent US 8,377,646
Granted Patent B2
US 8,377,646 · App. 13/243,593 · Granted Feb 19, 2013

Beta-2 microglobulin as a biomarker for peripheral artery disease

Inventors: John P. Cooke (Palo Alto, CA); Eric T. Fung (Austin, TX); Eiichiro Kimura (Kawasaki, JP)
Assignees: Vermillion, Inc.; Board of Trustees of the Leland Standford Junior University
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Quick Facts
Patent No.
US 8,377,646
App. No.
13/243,593
Granted
Feb 19, 2013
Kind
B2
Abstract

The present invention provides β2 microglobulin as a biomarker for qualifying or assessing peripheral artery disease in a subject.

Claims (5)

1. A method for qualifying peripheral artery disease status in a subject comprising:

(a) measuring cystatin C in a biological sample from the subject; and

(b) correlating the measurement or measurements with peripheral artery disease versus non-peripheral artery disease.

2. The method of claim 1 , further comprising measuring β2-microglobulin.

3. The method of any of claim 1 or claim 2 , wherein said measurement or measurements of a biomarker is performed using an immunoassay.

Assignments (1)
CONFIRMATORY LICENSE Recorded Sep 17, 2013
From: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 031218/0542 →
Continuity (5)
Division 12972867 · Dec 20, 2010
Division 11685146 · Mar 12, 2007
Provisional Application 60781403 · Mar 11, 2006
Provisional Application 60863951 · Nov 1, 2006
Related Publication 20120077708A1 · Mar 29, 2012