ADHESION PREVENTION FABRIC
The present invention is directed to an adhesion prevention fabric having a first absorbable oxidized regenerated cellulose nonwoven fabric and a second absorbable oxidized regenerated cellulose woven or knitted fabric. Further disclosed is an adhesion prevention fabric that is useful for adhesion prevention in the presence of blood.
1 . A device for adhesion prevention comprising a first absorbable nonwoven oxidized regenerated cellulose layer and a second absorbable woven oxidized regenerated cellulose layer attached to the first absorbable nonwoven oxidized regenerated cellulose layer.
2 . The device of claim 1 wherein the first nonwoven oxidized regenerated cellulose layer is an absorbable hemostat.
3 . The device of claim 1 wherein the second woven oxidized regenerated cellulose layer is an absorbable adhesion prevention barrier.
4 . The device of claim 1 wherein the first nonwoven oxidized regenerated cellulose layer is an absorbable hemostat and the second woven oxidized regenerated cellulose layer is an absorbable adhesion prevention barrier.
5 . The device of claim 2 wherein the absorbable hemostat has a carboxyl content of 18 to 21%.
6 . The device of claim 3 wherein the absorbable adhesion prevention barrier has a carboxyl content of 9% to 21%.
7 . The device of claim 4 wherein the absorbable hemostat has a carboxyl content of 18 to 21% and the absorbable adhesion prevention barrier has a carboxyl content of 9% to 21%.
8 . The device of claim 1 wherein the first absorbable nonwoven oxidized regenerated cellulose layer has a thickness of about 0.25 to 6 mm.
9 . The device of claim 1 wherein the first absorbable nonwoven oxidized regenerated cellulose layer has a basic weight of about 0.01 to 0.2 g/in 2 .
10 . The device of claim 1 wherein the first absorbable nonwoven oxidized regenerated cellulose layer has a weight percent from about 5 to 90 percent of a total weight of the device.
11 . A method of making a device for adhesion prevention comprising the steps of:
providing a regenerated cellulose woven fabric;
oxidizing the regenerated cellulose woven fabric with a solution of nitrogen dioxide in a perfluorocarbon solvent to achieve an oxidized regenerated cellulose woven fabric having a carboxyl content ranging from 9% to 21%;
providing an oxidized regenerated cellulose nonwoven fabric; and
attaching the oxidized regenerated cellulose nonwoven fabric to the oxidized regenerated cellulose woven fabric.
12 . The method of claim 11 wherein the oxidized regenerated cellulose woven fabric is an absorbable adhesion prevention barrier.
13 . The method of claim 11 wherein the oxidized regenerated cellulose nonwoven fabric is an absorbable hemostat.
14 . The method of claim 11 wherein the oxidized regenerated cellulose nonwoven fabric is an absorbable hemostat and the oxidized regenerated cellulose woven fabric is an absorbable adhesion prevention barrier.