Method and sample holding assembly for use in sample preparation
View Patent ↗A method and sample holding assembly are described for use in the preparation of samples for analysis. The method comprises the steps of collecting a sample in a concentration tube which is open at one end and closed at the other, the closed end being selectively openable. A vial is coupled to the open end, the tube is inverted, the closed end is opened, and then solvent is evaporated from the sample via the opened end until the concentrated sample is confined to the vial. A sample holding assembly for use in the present method is also described. It comprises a concentration tube, and an adaptor arrangement for coupling a vial to the open end of the tube and defining a fluid path between the tube and the vial.
1. A method of preparing a sample for analysis, wherein the sample comprises at least one solute in a solvent, using a concentration tube having first and second ends, the tube being open at the first end and closed at the second end, the second end being selectively openable, the method comprising the steps of:
inserting the first end of the concentration tube into a sample extraction system, with the second end being closed, and collecting a sample in the tube;
coupling a vial to the first end of the tube;
inverting the tube;
opening the second end of the tube; and
evaporating solvent from the sample via the second end of the tube, until the concentrated sample is confined to the vial.
2. A method of claim 1 , including the steps of decoupling the vial from the tube after the evaporation step, and loading the vial into analysis apparatus.
3. A method of claim 2 , wherein the analysis apparatus is chromatographic analysis apparatus.
4. A method of claim 1 , wherein the vial is a gas chromatography vial.
5. A method of claim 1 , wherein the coupling step comprises coupling the vial to the first end of the tube with an adaptor arrangement which defines a fluid path between the tube and the vial.
6. A method of claim 5 , wherein the adaptor arrangement comprises an adaptor having a tube end for coupling to the tube and a vial end for coupling to a vial, and a container for receiving a vial, the container being coupled with the vial end of the adaptor in the coupling step such that the open end of the vial is held in fluid communication with the fluid path through the adaptor arrangement.
7. A method of claim 6 , wherein the container and adaptor are coupled together by complementary screw threads, and the adaptor arrangement includes a seal configured so that as the container is screwed onto the adaptor, the open end of the vial held in the container is urged against the seal.
8. A method of claim 5 , wherein the adaptor and tube are coupled together by complementary screw threads.
9. A method of claim 5 , wherein the sample extraction system comprises a solvent extraction system.
10. A method of claim 1 , wherein the other end of the tube is closed by a removable cap and opened in the opening step by removing the cap.
11. A method of claim 10 , wherein the removable cap and tube are coupled together by complementary screw threads.