IP Library Granted Patent US 11,366,120
Granted Patent B2
US 11,366,120 · App. 13/261,787 · Granted Jun 21, 2022

Peptide capture and characterization

Inventors: Xiaolian Gao (Houston, TX); Xiaochuan Zhou (Houston, TX)
G01N33/6842B01L3/5027G01N33/574B01L2300/0816B01L2300/0819
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Quick Facts
Patent No.
US 11,366,120
App. No.
13/261,787
Granted
Jun 21, 2022
Kind
B2
Abstract

The invention relates to the measurement and profiling of proteins including phosphoproteins from cells in particular the measurement and profiling of phosphoproteins involved in cancer.

Claims (6)

1. A method for differential detection of phosphoprotein expression in cancerous and non-cancerous cells comprising:

a) making a microarray containing peptides that bind phosphoproteins;

b) lysing the cancerous cells and collecting proteins from the cells;

c) binding the phosphoproteins with peptides on the microarray;

d) detecting the phosphoproteins; and

e) repeating steps b-d using the non-cancerous cells and comparing the results.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 13, 2018
From: ZHOU, XIAOCHUAN
To: LC SCIENCES LC
Reel/Frame 045181/0521 →
Continuity (2)
Provisional Application 61520306 · Jun 8, 2011
Related Publication 20210318328A1 · Oct 14, 2021