Treatment of cutaneous hemangioma
View Patent ↗This invention concerns a method of treating hemangiomas with a beta blocker by applying the beta blocker onto the hemangiomas directly. The invention also concerns a combination therapy by using a beta blocker along with a corticosteroid or an alpha adrenergic receptor agonist for the treatment of hemangiomas.
1. A method of treating a cutaneous capillary hemangioma of an eye lid or orbit that is inducing mechanical ptosis in an infant patient, comprising applying a topical timolol formulation to said eye and said hemangioma, or a pharmaceutically acceptable salt thereof, in an amount effective to reduce the size of the hemangioma, periodically until the visual axis of said infant is cleared and the mechanical ptosis improves, wherein said effective amount maintains normal intraocular pressure of said eye and produces little to no local side effects or systemic complications.
2. The method according to claim 1 , wherein the topical timolol formulation is applied in a form of solution drops, gel, ointment, cream, spray, aerosol, or transdermal patch.
3. The method according to claim 1 , wherein the topical timolol formulation is a timolol solution.