Pelvic tissue support devices
View Patent ↗A delivery system is provided that is adapted to treat various urological pelvic disorders, such as prolapse, incontinence, and the like. The delivery system can include at least one biologic loaded or otherwise provided with a bioactive agent. The biologic can comprise any drugs, hormones or steroids, stem cells, growth factors, proteins, and/or other bioactive agents to promote cell or tissue growth for the treatment and strengthening of organ walls or tissue. The biologic is generally adapted to controllably release the agent to the surrounding tissue or organ to provide a local and targeted delivery.
1. A biologic delivery system for treating pelvic disorders in a patient, comprising:
a biologic that is a particularized non-chemically crosslinked porcine dermis loaded with a bioactive agent selected from the group consisting of a growth factor and a hormone;
a pelvic implant device adapted to support pelvic tissue of the patient and to deliver the loaded bioactive agent to a target tissue within the pelvic region of the patient, wherein the pelvic implant device is a pelvic sling constructed at least in part of a mesh material or a thin sheet, and the biologic is incorporated into or coated on the pelvic sling.
2. The system of claim 1 , wherein the bioactive agent includes a basic fibroblast growth factor.
3. The system of claim 1 , wherein the bioactive agent includes a hormone.
4. The system of claim 3 , wherein the hormone includes estrogen.
5. The system of claim 1 , wherein the bioactive includes a protein.
6. The system of claim 1 , wherein the pelvic implant device is a pelvic sling device constructed at least in part of a mesh material.
7. The system of claim 1 wherein the pelvic sling device is configured for the treatment of tissue or organ prolapse.
8. The system of claim 1 wherein the pelvic sling device is configured for the treatment of urinary incontinence.
9. A method of treating a pelvic disorder in a patient with a biologic delivery system, comprising:
providing
the pelvic implant device of claim 1 to a pelvic area in a patient; and
allowing the device to support pelvic tissue of the patient and to deliver the loaded bioactive agent to target tissue at the pelvic area of the patient to treat the pelvic disorder.
10. The method of claim 9 , wherein the bioactive agent includes a hormone.
11. The method of claim 9 , wherein the bioactive agent includes a growth factor.