Glucose sensor signal reliability analysis

1. An apparatus comprising:

a glucose sensor to obtain measurements responsive to a presence of glucose in a fluid; and

a processor to:

detect a change in responsiveness of said glucose sensor to said presence of glucose in a fluid based, at least in part, on an application of one or more thresholds to one or more sensitivity metrics,

at least one of said sensitivity metrics being computed based, at least part, on said measurements, wherein said change in responsiveness of said glucose sensor to the presence of glucose in said fluid is detected by:

defining a sequence of windows in time;

for at least one of said windows, computing a measure of dispersion of said rate of change; and

determining at least one of said sensitivity metrics based, at least in part, on said computed measure of dispersion; wherein said at least one of said sensitivity metrics are detected by determining said at least one of said sensitivity metrics based, at least in part, on a ratio of said computed measure of dispersion and a mean value of glucose sensor measurements obtained in said at least one of said windows.

2. The apparatus of claim 1 , wherein said change in responsiveness comprises a decrease in sensitivity of said glucose sensor to the presence of glucose in said fluid.

3. The apparatus of claim 1 , wherein said computed measure of dispersion of said rate of change comprises a variance of said rate of change.

4. An article comprising:

a non-transitory storage medium having machine-readable instructions stored thereon which are executable by a special purpose computing apparatus to:

obtain a plurality of glucose sensor measurements at a glucose sensor over a time interval; and

detect a change in responsiveness of said glucose sensor to a presence of glucose in a fluid based, at least in part, on an application of one or more thresholds to one or more sensitivity metrics, at least one of said sensitivity metrics being based, at least in part, on said glucose sensor measurements, wherein said change in responsiveness of said glucose sensor to the presence of glucose in said fluid is detected by:

defining a sequence of windows in time;

for at least one of said windows, computing a measure of dispersion of said rate of change; and

determining at least one of said sensitivity metrics based, at least in part, on said computed measure of dispersion; wherein said at least one of said sensitivity metrics are detected by determining said at least one of said sensitivity metrics based, at least in part, on a ratio of said computed measure of dispersion and a mean value of glucose sensor measurements obtained in said at least one of said windows.

5. The article of claim 4 , wherein said change in responsiveness comprises a decrease in sensitivity of said glucose sensor to the presence of glucose in said fluid.

6. The article of claim 4 , wherein said computed dispersion of said rate of change comprises a variance of said rate of change.

7. An apparatus comprising:

means for obtaining a plurality of glucose sensor measurements at a glucose sensor over a time interval; and

means for detecting a change in responsiveness of said glucose sensor to a presence of glucose in a fluid based, at least in part, on an application of one or more thresholds to one or more sensitivity metrics, at least one of said sensitivity metrics being based, at least in part, on said glucose sensor measurements, wherein said means for detecting a change in responsiveness of said glucose sensor to the presence of glucose in said fluid detects said change in responsiveness by defining a sequence of windows in time; for at least one of said windows, computing a dispersion of said rate of change; and determining at least one of said sensitivity metrics based, at least in part, on said computed dispersion; wherein said at least one of said sensitivity metrics are detected by determining said at least one of said sensitivity metrics based, at least in part, on a ratio of said computed dispersion and a mean value of glucose sensor measurements obtained in said at least one of said windows.