Method for producing monolithic tablets
View Patent ↗The present invention relates to a process for producing monolithic tablets. The method employs a melt-processed composition containing at least on active agent and at least one thermoplastic binder. The invention further relates to a method for cutting and deflashing a belt of pre-shaped bodies of a melt-processed composition, wherein the pre-shaped bodies are interconnected by flash.
1. A method for producing monolithic tablets, the method comprising the steps of:
a) providing a belt of pre-shaped bodies of a melt-processed composition, the pre-shaped bodies in said belt being interconnected by flash, each pre-shaped body having an predetermined weight;
b) cutting the interconnecting flash in the belt to obtain singulated pre-shaped bodies;
c) charging the singulated pre-shaped bodies into a die cavity; and
d) compressing the singulated pre-shaped bodies to simultaneously shape and deflash to obtain monolithic tablets,
wherein the pre-shaped bodies adopt the shape of the die surface upon compressing.
2. The method of claim 1 , wherein cutting and deflashing are performed sequentially.
3. The method of claim 1 , wherein cutting and deflashing are performed simultaneously.
4. The method of claim 1 wherein the pre-shaped bodies are a cylinder with hemispherical extremities.