Self emulsified compositions
View Patent ↗Provided are cosmetic compositions of incompatible cosmetic composition provided long term stability by the interfacial reaction of two immiscible polymers having complementary reactive pair functional groups.
1. An anhydrous emulsion composition comprising a continuous phase, a dispersed phase, and a compatibilizer present interfacially therebetween that is the reaction product of a first functional polymer dispersible in the continuous phase and a second functional polymer dispersible in the dispersed phase, the compatibilizer having at least one complementary reactive group pairing and being formed interfacially between the continuous and dispersed phases upon admixing of the continuous and dispersed phases each containing their respective first and second functional polymers dispersed therein to effect compatibilizer formation by in-situ reaction of said first and second polymers, and at least one of the continuous and dispersed phases containing a cosmetic active agent; wherein the complementary reactive group pairing is amine/cyclic anhydride.
2. The composition of claim 1 , wherein the first and second functional polymers are each independently natural or synthetic polymers.
3. The composition of claim 2 , wherein the natural polymers are selected from the group consisting of pullan, carrageen, glycon, cellulose, hydroxycellulose, amylose, chitosan, N,O-carboxymethylchitosan, algin and alginic acid, agar, pectin, starch, dextran, dextrin, cyclodextrin, konjac, glucomannan, chitin, pustulan, heparin, cardlan, hyaluronic acid, xantham, and combinations and derivatives thereof.
4. The composition of claim 2 , wherein the synthetic polymers are selected from the group consisting of a polyolefin, a polyether, a polyester, a polysiloxane, a polyamide, a polyacrylate, a polyurethane, a polyphosphazene, a polyvinylpyrolidone, or combinations thereof.
5. The composition of claim 1 , wherein the amine further includes aliphatic amines, aromatic amines, amino acids or peptides.
6. The composition of claim 5 , wherein the amine is an amino acid or peptide.
7. The composition of claim 1 , wherein the first functional polymer and/or the second functional polymer has two or more reactive functional groups thereon, each of the functional groups being identical in respect of each polymer.
8. The composition of claim 1 , wherein one of said first and second polymers has two or more different reactive functional groups thereon, said different reactive functional groups being adapted to form two or more different complementary reactive group pairings with the complementary reactive functional group on the other of the first and second polymers.
9. The composition of claim 1 , wherein both of said first and second polymers have two or more different reactive functional groups thereon, said different reactive functional groups forming two or more different complementary reactive group pairings with the respective complementary reactive functional groups on the other of the first and second polymers.
10. The composition of claim 1 , wherein one or both of said first and second functional polymers have a backbone chain and at least one reactive functional group is pendant to or end-capped on the backbone chain.
11. The composition of claim 10 , wherein the reactive functional group is pendant to the backbone.
12. The composition of claim 1 , wherein one or both of said first and second functional polymers have a backbone chain and at least one reactive functional group is within the backbone chain.
13. The composition of claim 1 , wherein the cosmetic active agent is selected from the group consisting of colorants, pigments, botanical extracts, antioxidants, emollients, humectants, moisturizers, sunscreens, keratolytics, depigmenting agents, retinoids, alpha-hydroxy acids, alpha-keto acids, lipidic compounds, anti-inflammatory agents, anti-irritants, anti-acne agents, insect repellents, skin protectants, skin penetration enhancers, exfollients, depigmenting agents, hypopigmenting agents, and compatible combinations thereof.
14. The composition of claim 13 , further comprising a compatible excipient selected from the group consisting of fillers, emulsifying agents, surfactant active agents, film formers, plasticizers, solvents, chelating agents, gelling agents, thickeners, anti-foaming agents, binders, bulking agents, pH adjusters, preservatives, fragrance, stabilizers, photostabilizing agents, viscosity and/or rheology modifiers, and compatible combinations thereof.
15. The composition of claim 1 , wherein the in-situ reaction does not produce a leaving group.
16. The composition of claim 1 , wherein the in-situ reaction occurs at a temperature range from about 20° C. to about 120° C.
17. The composition of claim 1 , wherein the in-situ reaction occurs at a pH of about 3.5 to about 9.5.
18. The composition of claim 1 , wherein the in-situ reaction occurs in about one minute to about one hour after the continuous phase and the disperse phase are admixed.
19. The composition of claim 18 , wherein the in-situ reaction is completed in about one minute to about ten minutes.
20. The composition of claim 1 , wherein the composition is an anhydrous emulsion selected from the group consisting of oil-in-silicone, silicone-in-oil, oil-in-oil, fluoropolymer-in-oils, oil-in-fluoropolymer, fluoropolymer-in-silicone, silicone-in-fluoropolymer emulsion, and polyol-in-oil.
21. The composition of claim 20 , wherein the anhydrous emulsion is further emulsified with a hydrous phase to form a double emulsion selected from the group consisting of silicone-in-oil-in-water, oil-in-silicone-in-water, fluoropolymer-in-silicone-in-water, silicone-in-fluoropolymer-in-water, fluoropolymer-in-oil-in-water, oil-in-fluoropolymer-in-water, and polyol-in-oil-in-water.
22. The composition of claim 1 , wherein said first functional polymer is a polydimethylsiloxane with an amine functional group, and said second functional polymer is a polyolefin with a cyclic anhydride group.