Antisense oligonucleotides for treating allergy and neoplastic cell proliferation
View Patent ↗Antisense oligonucleotides for treating and/or preventing at least one of asthma, allergy, hypereosinophilia, general inflammation and cancer are provided. The oligonucleotides are directed against nucleic acid sequences coding for a receptor selected from the group consisting of a CCR3 receptor and a common sub-unit of IL-3, IL-5 and GM-CSF receptors.
1. A pharmaceutical composition comprising two oligonucleotides consisting of SEQ ID NO. 13 and SEQ ID NO. 14 and a pharmaceutically acceptable carrier.
2. The pharmaceutical composition of claim 1 , wherein the pharmaceutical composition is topical.
3. A method for treating asthma in a subject, comprising the step of administering to the subject an effective amount of the pharmaceutical comprising two oligonucleotides consisting of SEQ ID NO. 13 and SEQ ID NO. 14.
4. The method of claim 3 , wherein the method is for treating asthma.