Granted Patent B2

US 8,491,472 · App. 13/304,055 · Granted Jul 23, 2013

Abstract

Claims (40)

1. A submucosal implant system comprising:

a) a safe access needle injection means having a needle member adapted to pierce a mucosal tissue and deliver fluid to a submucosal layer;

b) a submucosal tunneling means including an elongate tubular member having proximal and distal ends and a lumen extending therethrough and an expandable member having first and second ends wherein said first end of said expandable member is attached to said distal end of said tubular member and said second end of said expandable member is everted and positioned within said lumen of said tubular member,

wherein said distal end of said elongate tubular member is adapted to enter an opening through the mucosal layer and into the submucosal layer of a mammal;

c) a submucosal dissection means including an elongate tubular member having proximal and distal sections and an expandable member disposed at said distal section of said tubular member; and,

d) an implantable therapeutic agent delivery device.

2. A submucosal implant system according to claim 1 wherein said safe access needle injection means comprises:

an elongate tubular member having proximal and distal ends and a lumen extending therethrough;

a tissue holding member positioned adjacent the distal end of said elongate tubular member and is adapted to engage a desired region of a mucosal layer; and,

said needle member having a lumen wherein said needle member is slidably disposed within the lumen of said elongate tubular member and adapted to pierce a desired region of the mucosal layer engaged by said tissue holding member and enter the submucosal layer such that delivery of a fluid through the lumen of said needle member enters said submucosal layer to thereby elevate said desired region of the mucosal layer.

3. A submucosal implant system according to claim 1 wherein said submucosal dissecting means comprises an elongate tubular member having proximal and distal sections and an expandable member disposed at the distal section of said tubular member.

4. A submucosal implant system according to claim 1 wherein said submucosal tunneling means and said submucosal dissecting means are integrally formed.

5. A submucosal implant system according to claim 1 wherein said implantable therapeutic agent delivery device includes an anchor.

6. A submucosal implant system, comprising:

a) a safe access needle injection means having a needle member adapted to pierce mucosal tissue and deliver fluid to the submucosal layer;

b) a submucosal tunneling means including an elongate tubular member having proximal and distal ends and a lumen extending therethrough, and an expandable member having first and second ends wherein said first end of said expandable member is attached to said distal end of said tubular member and said second end of said expandable member is everted and positioned within said lumen of the tubular member,

wherein the distal end of said elongate tubular member is adapted to enter an opening through the mucosal layer and into the submucosal layer of a mammal;

c) a submucosal dissection means including an elongate tubular member having proximal and distal sections and an expandable member disposed at the distal section of said tubular member; and,

d) an implantable drug delivery device.

7. A submucosal implant system according to claim 6 wherein said safe access needle injection means comprises:

an elongate tubular member having proximal and distal ends and a lumen extending therethrough;

a tissue holding member positioned adjacent the distal end of said elongate tubular member and is adapted to engage a desired region of a mucosal layer; and,

said needle member having a lumen wherein said needle member is slidably disposed within the lumen of said elongate tubular member and adapted to pierce a desired region of the mucosal layer engaged by said tissue holding member and enter the submucosal layer such that delivery of a fluid through the lumen of said needle member enters said submucosal layer to thereby elevate said desired region of the mucosal layer.

8. A submucosal implant system according to claim 6 wherein said implantable drug delivery device includes an anchor.

9. A submucosal implant system, comprising:

a) a safe access needle injection instrument having a needle member adapted to pierce mucosal tissue and deliver fluid to the submucosal layer;

b) a submucosal tunneling device having an expandable, evertable distal end;

c) a submucosal dissection device having an expandable distal end,

wherein each of said tunneling device and said dissection device has a closed distal end; and

d) an implantable drug delivery device.

10. A submucosal implant system according to claim 9 wherein said distal end of said tunneling device is longitudinally expanding, and said distal end of said dissection device is laterally expandable.

11. A submucosal implant system according to claim 9 wherein said implantable drug delivery device includes an anchor.

12. A submucosal implant system according to claim 11 wherein said implantable drug delivery device includes an anchor.

13. A submucosal implant system, comprising:

a) a safe access needle injection means having a needle member adapted to pierce mucosal tissue and deliver fluid to the submucosal layer;

b) a submucosal tunneling means having a distal end with a longitudinally expandable, evertable tip;

c) a submucosal dissection means including an elongate tubular member having proximal and distal sections, an expandable member disposed at said distal section of said tubular member, and an open distal end,

wherein said expandable tip of said tunneling means is longitudinally displaceable through said open distal end and relative to said expandable member of said dissection means; and

d) an implantable drug delivery device.

14. A submucosal implant system according to claim 13 , wherein said submucosal tunneling means and said submucosal dissecting means are integrally formed.

Assignments (10)