Extended pain relief via high frequency spinal cord modulation, and associated systems and methods
View Patent ↗Extended pain relief via high frequency spinal cord modulation, and associated systems and methods. A method for treating a patient in accordance with a particular embodiment includes selecting a neural modulation site to include at least one of a dorsal root entry zone and dorsal horn of the patient's spinal cord, and selecting parameters of a neural modulation signal to reduce patient pain for a period of time after ceasing delivery of the signals, the period of time being at least one tenth of one second.
1. A patient treatment method, comprising:
selecting a neural modulation site to include a dorsal horn of a spinal cord of the patient; and
desensitizing a wide dynamic range neuron at the dorsal horn by applying to the dorsal horn a non-paresthesia producing neural modulation signal having a signal frequency in a range of from about 1.5 kHz to about 100 kHz, to address patient pain, the pain being addressed for a period of time after at least reducing an intensity of the signal, the period of time being at least one tenth of one second.
2. The method of claim 1 wherein the signal frequency is in a range of from about 3 kHz to about 100 kHz.
3. The method of claim 1 wherein the period of time is up to about one day.
4. The method of claim 1 , further comprising reducing afferent signals transmitted by neurons at the dorsal horn.
5. The method of claim 1 , further comprising programming a patient therapy device to deliver the neural modulation signal in accordance with selected parameters.
6. The method of claim 1 wherein the period of time is a period of time after ceasing delivery of the signals.
7. The method of claim 1 wherein the pain is addressed for the period of time after at least reducing the intensity of the signal without a patient-detectable change in a therapeutic efficacy of the signal.
8. The method of claim 1 wherein the pain is addressed for the period of time after at least reducing the intensity of the signal without a decrease in a pain-reducing effect of the signal when the signal intensity is reduced.
9. The method of claim 1 wherein the signal has pulses with a pulse width of from about 33 microseconds to about 100 microseconds.
10. A patient treatment method, comprising:
selecting a neural modulation site to include a dorsal horn of a spinal cord of the patient; and
desensitizing a wide dynamic range neuron at the dorsal horn by applying to the dorsal horn a non-paresthesia producing neural modulation signal having a frequency of from about 3 kHz to about 100 kHz to reduce patient pain.
11. The method of claim 10 wherein the neural modulation signal has at least approximately no effect on the patient's normal sensory functions.
12. The method of claim 10 wherein the neural modulation signal has at least approximately no effect on the patient's normal motor activity.
13. The method of claim 10 wherein the neural modulation signal has at least approximately no effect on the patient's normal proprioception.
14. The method of claim 10 wherein the signal frequency is in a range of from about 3 kHz to about 20 kHz.
15. The method of claim 10 wherein the signal frequency is in a range of from about 3 kHz to about 15 kHz.
16. The method of claim 10 wherein the signal frequency is in a range of from about 5 kHz to about 15 kHz.
17. The method of claim 10 wherein the signal frequency is in a range of from about 3 kHz to about 10 kHz.
18. The method of claim 10 wherein the signal has pulses with a pulse width of from about 10 microseconds to about 333 microseconds.
19. The method of claim 10 wherein the signal has pulses with a pulse width of from about 33 microseconds to about 100 microseconds.
20. The method of claim 10 wherein the signal has a frequency of from about 5 kHz to about 15 kHz and a pulse width of from about 25 microseconds to about 166 microseconds.