Electrowetting dispensing devices and related methods
View Patent ↗A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.
1. A method for dispensing liquid to a plurality of reservoirs, the method comprising:
positioning, via electrowetting, liquid to be dispensed, the positioning comprising aligning the liquid with a plurality of predetermined locations; and
dispensing, using centrifugation, the aligned liquid from the plurality of predetermined locations to the plurality of reservoirs through a plurality of openings respectively aligned with the predetermined locations.
2. The method of claim 1 , further comprising dividing the liquid into a plurality of individual portions via electrowetting, wherein the positioning comprises aligning each of the plurality of individual portions with the plurality of predetermined locations.
3. The method of claim 1 , wherein the dispensing the aligned liquid comprises dispensing the aligned liquid through a plurality of openings of a plurality of nozzles.
4. The method of claim 3 , further comprising spotting the liquid to a testing platform via the plurality of nozzles.
5. The method of claim 1 , wherein the dispensing the aligned liquid to a plurality of reservoirs comprises dispensing the aligned liquid to a plurality of reservoirs coated with a hydrophilic material.
6. The method of claim 1 , wherein the reservoirs comprise hydrophilic capillary tubes.
7. The method of claim 1 , wherein the dispensing the liquid to a plurality of reservoirs comprises dispensing the liquid to a plurality of wells in a titer plate.
8. A system for dispensing liquid to a plurality of reservoirs, the system comprising:
electrodes configured to position, via electrowetting, liquid to be dispensed, the positioning comprising aligning the liquid with a plurality of predetermined locations; and
a dispenser configured to dispense, using centrifugation, the aligned liquid from the plurality of predetermined locations to the plurality of reservoirs through a plurality of openings respectively aligned with the predetermined locations.
9. The system of claim 8 , further comprising a partitioner configured to divide the liquid into a plurality of individual portions via electrowetting, wherein the electrodes are further configured to align each of the plurality of individual portions with the plurality of predetermined locations.
10. The system of claim 8 , wherein the electrodes is configured to align liquid by dispensing the aligned liquid through the dispenser, wherein the dispenser includes a plurality of openings of a plurality of nozzles.
11. The system of claim 10 , wherein the dispenser is further configured to spot the liquid to a testing platform via the plurality of nozzles.
12. The system of claim 8 , wherein the plurality of reservoirs is coated with a hydrophilic material.