USE OF HIGH-DOSES OF MONOMERIC CONTRAST MEDIUM CONTAINING IODINE IN X-RAY DIAGNOSTICS, IN PARTICULAR IN INTERVENTIONAL X-RAY DIAGNOSTICS AND IN RADIATION THERAPY ASSISTED BY CONTRAST MEDIA CONTAINING IODINE
The invention relates to a diagnostic or therapeutic composition comprising a monomeric X-ray contrast medium containing iodine, in particular iopromide, for use in an X-ray assisted diagnosis or therapy and for the use of high doses of an X-ray contrast medium given to a patient, in particular patients with restricted kidney function.
1 . A diagnostic or therapeutic composition comprising a monomeric iodine-containing X-ray contrast medium for X-ray-supported diagnosis or treatment for the high-dose use of X-ray contrast medium.
2 . (canceled)
3 . (canceled)
4 . The diagnostic or therapeutic composition as claimed in claim 1 , wherein the X-ray contrast medium is selected from the group consisting of iopromide, iohexyl, iomeprol, and iopamidol.
5 . The diagnostic or therapeutic composition as claimed in claim 4 , wherein the X-ray contrast medium is iopromide.
6 . A method for X-ray-supported diagnosis or treatment in the high-dose use of X-ray contrast medium in a patient, comprising administering to the patient the composition of claim 1 .
7 . The method as claimed in claim 6 , wherein the composition comprises iopromide and is administered in a dose from 0.6 g of iodine per kg of body weight to 2 g of iodine per kg of body weight.
8 . The method as claimed in claim 6 , wherein the composition is administered in a dose from 1 g of iodine per kg of body weight to 7 g of iodine per kg of body weight.
9 . (canceled)
10 . (canceled)
11 . (canceled)
12 . The method for preparing a diagnostic or therapeutic composition as claimed in claim 9 , wherein the X-ray contrast medium is selected from the group consisting of iopromide, iohexyl, iomeprol, and iopamidol.
13 . The method for preparing a diagnostic or therapeutic composition as claimed in claim 12 , wherein the X-ray contrast medium is iopromide.
14 . A method of X-ray-supported diagnosis or treatment comprising administering to a patient in need thereof a monomeric iodine-containing X-ray contrast medium in an amount of from 0.6 g of iodine per kg of body weight to 7 g of iodine per kg of body weight.
15 . The method as claimed in claim 14 , wherein the X-ray contrast medium is administered in an amount of from 0.6 g of iodine per kg of body weight to 2 g of iodine per kg of body weight.
16 . The method as claimed in claim 14 , wherein the X-ray contrast medium is administered in an amount of from 1 g of iodine per kg of body weight to 7 g of iodine per kg of body weight.
17 . The method as claimed in claim 15 , wherein the patient has limited renal function or kidney failure.
18 . The method as claimed in claim 15 , wherein the X-ray contrast medium is selected from the group consisting of iopromide, iohexyl, iomeprol, and iopamidol.
19 . The method as claimed in claim 15 , wherein the X-ray contrast medium is iopromide.
20 . The method as claimed in claim 16 , wherein the patient has limited renal function or kidney failure.
21 . The method as claimed in claim 16 , wherein the X-ray contrast medium is selected from the group consisting of iopromide, iohexyl, iomeprol, and iopamidol.
22 . The method as claimed in claim 16 , wherein the X-ray contrast medium is iopromide.
23 . A method of preventing nephropathies in a patient for whom X-ray-supported diagnosis or treatment is indicated comprising administering to the patient a monomeric iodine-containing X-ray contrast medium in an amount of from 0.6 g of iodine per kg of body weight to 7 g of iodine per kg of body weight.
24 . The method as claimed in claim 23 , wherein the X-ray contrast medium is selected from the group consisting of iopromide, iohexyl, iomeprol, and iopamidol.
25 . The method as claimed in claim 23 , wherein the X-ray contrast medium is iopromide.