ADHESIVE-BASED VARICOSE VEIN TREATMENT
An intraluminal member can be used to deliver an adhesive to a vein while causing the vein to spasm, thereby controlling adhesive migration and improving procedure efficacy.
1 . A method of permanently occluding a vein through the combined spasm of the vein and injection of an adhesive, comprising the following steps:
advancing an elongated intraluminal member from an access site and into the vein, wherein the intraluminal member comprises a perturbing portion configured to perturb an inner vessel wall of the vein under user control when performing a defined movement;
perturbing the inner vessel wall by performing the defined movement of the perturbing portion of the intraluminal member, thereby inducing a region of the vein to spasm and reduce its diameter; and
injecting sufficient adhesive at or near the reduced-diameter region of the vein to occlude the vein permanently.
2 . The method of claim 1 , wherein the adhesive is injected in such as manner as to occlude the vein at a location distal to the region of spasm.
3 . The method of claim 1 , wherein the adhesive is injected in such as manner as to occlude the vein at a location proximal to the area of spasm.
4 . The method of claim 1 , wherein the perturbing portion is a tip of a wire and the defined movement includes rotating the tip so that the tip contacts the inner vessel wall.
5 . The method of claim 4 , wherein the defined movement further comprises moving the tip of the wire longitudinally along the vein.
6 . The method of claim 5 , wherein the tip of the wire is simultaneously rotated and moved longitudinally.
7 . The method of claim 4 , wherein the wire tip has a blade configuration that generates backflow of blood in the vessel when the wire is rotated.
8 . The method of claim 1 , further comprising injecting sclerosant at or near the reduced- diameter region of the vein.
9 . The method of claim 8 , wherein the sclerosant and the adhesive are injected simultaneously.
10 . The method of claim 8 , wherein the sclerosant is injected first, and the adhesive is injected after the sclerosant.
11 . The method of claim 8 , wherein the adhesive is injected first, and the sclerosant is injected after the adhesive.
12 . The method of claim 1 , further comprising observing the treatment site and waiting to inject the adhesive until a reduction in the vein diameter is observed.
13 . The method of claim 12 , wherein observing comprises ultrasound imaging.
14 . The method of claim 1 , further comprising exposing the adhesive to UV light so as to cure the adhesive.
15 . The method of claim 1 , further comprising applying external compression on the catheter tip before, during, or after injection of sclerosant.
16 . The method of claim 15 , wherein the external compression is applied with an ultrasound probe.
17 . Method of claim 15 , wherein the spasm is accentuated by external compression on the catheter tip at the injection site with the palm of the operator.
18 . The method of claim 15 , wherein the adhesive is injected in such as manner as to occlude the vein at a location distal to the region of spasm.
19 . The method of claim 15 , wherein the adhesive is injected in such as manner as to occlude the vein at a location proximal to the area of spasm.
20 . The method of claim 15 , wherein the perturbing portion is a tip of a wire and the defined movement includes rotating the tip so that the tip contacts the inner vessel wall.
21 . The method of claim 20 , wherein the defined movement further comprises moving the tip of the wire longitudinally along the vein.
22 . The method of claim 21 , wherein the tip of the wire is simultaneously rotated and moved longitudinally.
23 . The method of claim 20 , wherein the wire tip has a blade configuration that generates backflow of blood in the vessel when the wire is rotated.
24 . The method of claim 15 , further comprising injecting sclerosant at or near the reduced-diameter region of the vein.
25 . The method of claim 24 , wherein the sclerosant and the adhesive are injected simultaneously.
26 . The method of claim 24 , wherein the sclerosant is injected first, and the adhesive is injected after the sclerosant.
27 . The method of claim 24 , wherein the adhesive is injected first, and the sclerosant is injected after the adhesive.
28 . The method of claim 1 , further comprising observing the treatment site and waiting to inject the adhesive until a reduction in the vein diameter is observed.
29 . The method of claim 28 , wherein observing comprises ultrasound imaging.
30 . The method of claim 15 , further comprising exposing the adhesive to UV light so as to cure the adhesive.