System and method for fusing three dimensional image data from a plurality of different imaging systems for use in diagnostic imaging
View Patent ↗A multi-modality cancer screening and diagnosis system is provided that allows cancer screening and diagnosis of a patient using at least two different and sequential three-dimensional imaging techniques without patient repositioning. The system includes a first three-dimensional image acquisition device, a second three-dimensional image acquisition device having a probe with a transmitter mounted thereon, and a positioning paddle for positioning and immobilizing an object to be imaged during the cancer screening and diagnosis procedure. The positioning paddle is designed to facilitate visualization of the breast in both three-dimensional modalities without movement of the patient, and preferably is designed to position the patient with comfort during a diagnosis procedure which uses both imaging modalities.
1. A method of examining a breast of a patient includes the steps of:
immobilizing the breast, and while the breast is immobilized:
acquiring a three dimensional image of the breast using a first imaging modality, wherein the three dimensional image of the breast acquired using the first imaging modality has a first co-ordinate space;
selecting a region of interest (ROI) in a three dimensional volume based on the three dimensional image, the step of selecting including identifying coordinates of the ROI in the three dimensional volume;
acquiring a plurality of images of the breast using a second imaging modality through a manually-manipulable imaging probe, wherein the plurality of images of the breast acquired using the second imaging modality have a second co-ordinate space, the second co-ordinate space different than the first co-ordinate space;
tracking a movement of an imaging probe of the second imaging modality so as to obtain a second co-ordinate data of the second co-ordinate space, wherein tracking the movement of the imaging probe is performed during acquisition of the plurality of images of the breast with the second imaging modality;
co-registering the second coordinate data with the first co-ordinate space via a navigation system, the navigation system configured to transform a position and orientation of a field of view of the imaging probe of the second imaging modality so that the navigation system co-registers the second coordinate data with the three dimensional image;
during manual manipulation of the imaging probe during acquisition of the plurality of images of the breast with the second imaging modality, providing a cue indicating that the imaging probe is approaching the ROI identified in the three dimensional volume based on the co-registered second coordinate data and the three-dimensional image acquired by the first imaging modality; and
releasing the breast from immobilization.
2. The method of claim 1 wherein the first imaging modality is selected from a group of imaging modalities including tomosynthesis, computed tomography, SPECT, PET and gamma imaging.
3. The method of claim 1 wherein the second imaging modality includes ultrasound imaging.
4. The method of claim 1 wherein the step of selecting the ROI is performed manually.
5. The method of claim 1 wherein the step of selecting the ROI is performed with Computer Assisted Detection (CAD) assistance.
6. The method of claim 1 wherein the step of immobilizing the breast includes the step of positioning a positioning paddle over the breast, the positioning paddle comprising a porous fabric.
7. The method of claim 6 wherein the step of immobilizing the breast includes the step of tightening the fabric over the breast.
8. The method of claim 1 , wherein the cue is a visual or audible cue and the cue is provided when the imaging probe is directed to the coordinates of the ROI.
9. The method of claim 1 further comprising determining an orientation plane of the imaging probe, and reconstructing the three dimensional volume along the orientation plane of the imaging probe.
10. The method of claim 1 , wherein the cue is an audible cue.